Irritable bowel syndrome is a common disorder that exacts a significant toll on quality of life. For the first time, the American College of Gastroenterology has published guidelines on the diagnosis and treatment for this disorder.This episode is accredited for CPE. Subscribe at CEimpact( https://www.ceimpact.com/pharmacist ) and claim your CE today!Reference: Lacy, Brian E. PhD, MD, FACG1; Pimentel, Mark MD, FACG2; Brenner, Darren M. MD, FACG3; Chey, William D. MD, FACG4; Keefer, Laurie A. PhD5; Long, Millie D. MDMPH, FACG (GRADE Methodologist)6; Moshiree, Baha MD, MSc, FACG7 ACG Clinical Guideline: Management of Irritable Bowel Syndrome, The American Journal of Gastroenterology: January 2021 - Volume 116 - Issue 1 - p 17-44 doi: 10.14309/ajg.0000000000001036.Accessed at https://journals.lww.com/ajg/Fulltext/2021/01000/ACG_Clinical_Guideline__Management_of_Irritable.11.aspx Bristol stool scale (recommend tertiary references): Lewis, SJ; Heaton, KW (September 1997). "Stool form scale as a useful guide to intestinal transit time". Scand. J. Gastroenterol. 32 (9): 920–4. doi:10.3109/00365529709011203. PMID 9299672.CPE details for GameChangers Podcast February 2021Learning Objective: Discuss appropriate treatments for irritable bowel syndrome0107-0000-21-083-H01-P0.2 CEU/2.0 Hrs (Knowledge)Initial Release Date: 02/23/21Expiration Date: 02/23/24Additional CPE information is located at https://www.ceimpact.com/podcast See omnystudio.com/listener for privacy information.

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Lyme disease is a complex infection and post infection syndrome can lead to serious outcomes, including death. A new guideline was developed for the diagnosis and treatment of this infection. Spoon!This episode is accredited for CPE. Subscribe at CEimpact( https://www.ceimpact.com/pharmacist ) and claim your CE today!Reference: Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA), American Academy of Neurology (AAN), and American College of Rheumatology (ACR): 2020 Guidelines for the Prevention, Diagnosis and Treatment of Lyme Disease. Clinical Infectious Diseases, November 30, 2020. https://doi.org/10.1093/cid/ciaa1215. Accessed athttps://www.idsociety.org/practice-guideline/lyme-disease/ CPE details for GameChangers Podcast February 2021Learning Objective: Discuss treatment for different forms of lyme disease infections depending on the severity of symptoms0107-0000-21-XXX-H01-P0.2 CEU/2.0 Hrs (Knowledge)Initial Release Date: 02/23/21Expiration Date: 02/23/24Additional CPE information is located at https://www.ceimpact.com/podcast See omnystudio.com/listener for privacy information.

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In December 2020, the American College of Cardiology published an Expert Consensus Decision Pathway for Antithrombotic Therapy in Patients undergoing Percutaneous Coronary Intervention. This guideline addresses a timely problem of patients on anticoagulation and antiplatelet therapy.This episode is accredited for CPE. Subscribe at CEimpact ( https://www.ceimpact.com/pharmacist ) and claim your CE today!Reference: 2020 ACC Expert Consensus Decision Pathway for Anticoagulant and Antiplatelet Therapy in Patients With Atrial Fibrillation or Venous Thromboembolism Undergoing Percutaneous Coronary Intervention or With Atherosclerotic Cardiovascular Disease: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. Dec 18, 2020. Epublished DOI: 10.1016/j.jacc.2020.09.011. Accessed at https://www.jacc.org/doi/10.1016/j.jacc.2020.09.011CPE details for GameChangers Podcast January 2021Learning Objective: Recommend an appropriate antithrombotic/anticoagulant regimen in a patient who has received percutaneous coronary intervention with stenting0107-0000-21-079-H01-P0.2 CEU/2.0 Hrs (Knowledge)Initial Release Date: 01/25/21Expiration Date: 01/26/24Additional CPE information is located at https://www.ceimpact.com/podcastSee omnystudio.com/listener for privacy information.

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The unbelievable happened in 2020 - a vaccine was developed with high efficacy within 12 months for a novel virus! In December two vaccines for the prevention of the SARS-CoV-2 virus were approved through Emergency Use Authorization in the US. Is it time to get a shot?This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!Reference: Polack F, Thomas S, Kitchin N, et al. Safety and Efficacy of the BNT162b2 mRNA COVID-19 Vaccine. NEJM. Dec 10, 2020. DOI: 10.1056/NEJM2034577Baden L, El Sahly H, Essink B, et al. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. NEJM. Dec 30, 2020. DOI: 10.1056/NEHMoa2035389ACIP Recommendations: https://www.cdc.gov/vaccines/hcp/acip-recs/vacc-specific/covid-19.html See omnystudio.com/listener for privacy information.

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Every December, the American Diabetes Association updates the Standards of Medical Care in Diabetes. The guidelines cover sixteen sections from diabetes advocacy to technology updates. Start 2021 off right - learn what changed and what matters most for individuals with diabetes.This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!Reference: American Diabetes Association. Standards of Medical Care in Diabetes - 2021. Diabetes Cares. January 01, 2021; volume 44, issue supplement 1. https://care.diabetesjournals.org/content/44/Supplement_1 Disclosure: Dr. Jake Galdo is a speaker for Novo Nordisk in 2021.See omnystudio.com/listener for privacy information.

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Myopathy is a common reason for discontinuation of statin medications. The recent SAMSON study examined the nocebo effect and how this may bias patients towards treatment failure. How can clinicians overcome the nocebo effect?This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!Reference: Wood F, Howard J, Finegold J, et al. N-of-1 Trial of a Statin, Placebo, or No Treatment to Assess Side Effects. N Engl J Med 2020; 383:2182-2184. DOI: 10.1056/NEJMc2031173See omnystudio.com/listener for privacy information.

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The efficacy of antiretroviral therapy has led to persons with HIV living a near-normal lifespan. But medications only work when used appropriately. The International Antiviral Society-USA Panel published updated recommendations for the treatment and prevention of HIV infections. Treatment of HIV may be distilled into a simple idea - two "nucs" and something else. Learn how to optimize care for your patients.This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!Reference: Saag MS, Gandhi RT, Hoy JF, et al. Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2020 recommendations of the International Antiviral Society-USA Panel. JAMA. 2020;324(16):1651-1669. Available at: https://www.iasusa.org/2020/11/12/antiretroviral-drugs-treatment-prevention-hiv-infection-adults-2020-recommendations-of-the-international-antiviral-society-usa-panel/ The CE for this episode is supported by an educational grant from Xellia Pharmaceuticals, a specialty pharmaceutical company focused on providing important anti-infective treatments against serious and often life-threatening infections. See omnystudio.com/listener for privacy information.

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Clostridioides difficile is an important cause of morbidity and mortality in the United States with over 500,000 infections annually. The Infectious Disease Society of America released a clinical quality measure focused on treatment of c diff in March 2020. A review of the diagnosis and treatment will help providers improve quality.This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!The CE for this episode is supported by an educational grant from Xellia Pharmaceuticals, a specialty pharmaceutical company focused on providing important anti-infective treatments against serious and often life-threatening infections. See omnystudio.com/listener for privacy information.

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The question of acetaminophen versus ibuprofen may finally be laid to rest. A recent meta-analysis compared the efficacy and safety of ibuprofen versus acetaminophen for the treatment of fever or pain in children younger than 2 years. Is there a drug of choice?Reference: Tan E, Braithwaite I, McKinlay CJD, Dalziel SR. Comparison of Acetaminophen (Paracetamol) With Ibuprofen for Treatment of Fever or Pain in Children Younger Than 2 Years: A Systematic Review and Meta-analysis. JAMA Netw Open. 2020;3(10):e2022398. doi:10.1001/jamanetworkopen.2020.22398This episode is accredited for CPE. Subscribe at CEimpact (https://www.ceimpact.com/pharmacist) and claim your CE today!The CE for this episode is supported by an educational grant from Xellia Pharmaceuticals, a specialty pharmaceutical company focused on providing important anti-infective treatments against serious and often life-threatening infections. See omnystudio.com/listener for privacy information.

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In the never ending battle with COVID-19, new studies have demonstrated a role for IVIG in the treatment of acute COVID-19 pneumonia, the potential benefit of honey and black seed in mild to moderate COVID-19, and the efficacy of an mRNA vaccine. What does this all mean for current practice?Additional References:IVIG: Gharebaghi, N., Nejadrahim, R., Mousavi, S.J. et al. The use of intravenous immunoglobulin gamma for the treatment of severe coronavirus disease 2019: a randomized placebo-controlled double-blind clinical trial. BMC Infect Dis 20, 786 (2020). https://doi.org/10.1186/s12879-020-05507-4 Honey: Ashraf S, Ashraf S, Imran M, et al. Efficacy of honey and Nigella sativa against COVID-19: HNS-COVID-PK Trial. medRxiv 2020.10.30.20217364; doi: https://doi.org/10.1101/2020.10.30.20217364 Cleveland Clinic Hospitalization Risk for COVID-19 Positive Calculator: https://riskcalc.org/COVID19Hospitalization/ Cleveland Clinic Predict COVID-19 test result Calculator: https://riskcalc.org/COVID19/ This episode is accredited for CPE. Subscribe at CEimpact https://www.ceimpact.com/pharmacist and claim your CE today!The CE for this episode is supported by an educational grant from Xellia Pharmaceuticals, a specialty pharmaceutical company focused on providing important anti-infective treatments against serious and often life-threatening infections. See omnystudio.com/listener for privacy information.

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