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In episode 613, Mike and James discuss with Jessica Kirkwood the evidence for post-exposure prophylaxis of sexually transmitted infections. We go over the 4 RCTs that have looked at the value of a single dose of doxycycline. It does reduce the risk for some specific infections – but as always you need to know the numbers. We give you all of them and much, much more.
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BS Medicine Episode #613: Doxycycline for post-exposure prophylaxis of sexually transmitted infections - CFPCLearn
In episode 611, Tina and James talk with Samantha Moe about the use of betablockers and other medications for essential tremor. There is some evidence – much of it from the 1970s, but also some more recent publications. We do our best to tease out all the numbers you need to help you with your recommendations.
Show Notes
Tools For Practice Meds for Essential Tremor: Steady solution or shaky science?
In episode 610, Jamie and James chat with Jennifer Young about yet another Vitamin D Tools for Practice. We look at what happens to mortality, CVD and cancer when Vitamin D supplements are compared to placebo. The results may surprise you – or maybe not if you have listened to previous BS Medicine Podcasts on this seemingly never-ending topic.
Show Notes
Tools For Practice Vitamin D and Mortality – Don't bet your life on it!
Vitamin D and Respiratory Tract Infections: Does the sun's vitamin chase the cold?
Un nouvel épisode du Pharmascope est maintenant disponible! Dans de ce 115ème épisode, Sébastien, Nicolas et Isabelle terminent leur série d'épisodes sur l'ostéoporose. Dans cette troisième et dernière partie, on aborde la prise en charge suite à une fracture, les marqueurs du remodelage osseux, l'ostéoporose induite par les corticostéroïdes et la prise concomitante de suppléments de calcium et de vitamine D lors de l'utilisation d'un traitement pharmacologique.
Les objectifs pour cet épisode sont les suivants:
Ressources pertinentes en lien avec l'épisode
Qaseem A et coll; Clinical Guidelines Committee of the American College of Physicians. Pharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults: A Living Clinical Guideline From the American College of Physicians. Ann Intern Med. 2023;176:224-38.
National Osteoporosis Guideline Group – UK. Clinical Guideline for the Prevention and Treatment of Osteoporosis 2021. Septembre 2021.
Moe S, Paige A, Allan GM. Osteoporosis in postmenopausal women. Can Fam Physician. 2021;67:346.
Nayak S, Greenspan SL. Osteoporosis Treatment Efficacy for Men: A Systematic Review and Meta-Analysis. J Am Geriatr Soc. 2017;65:490-95.
National Institute for Health and Care Excellence (NICE). Osteoporosis: assessing the risk of fragility fracture. London; 2017.
Papaioannou A et coll. 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary. CMAJ. 2010;182:1864-73.
Management of Osteoporosis in Postmenopausal Women: The 2021 Position Statement of The North American Menopause Society'' Editorial Panel. Management of osteoporosis in postmenopausal women: the 2021 position statement of The North American Menopause Society. Menopause. 2021;28:973-97.
Bessette L et coll. The care gap in diagnosis and treatment of women with a fragility fracture. Osteoporos Int. 2008;19:79-86.
Deng J et coll. Pharmacological prevention of fractures in patients undergoing glucocorticoid therapies: a systematic review and network meta-analysis. Rheumatology. 2021;60:649-57.
Calculateur FRAX Centre for Metabolic Bone Diseases. FRAX: Fracture Risk Assessment Tool. University of Sheffield, UK.
Outil d'aide à la décision Mayo Foundation for Medical Education and Research. Bone Health Choice Decision Aid. Mayo Clinic, USA.
Holala! Un premier épisode du Pharmascope enregistré devant public est maintenant disponible! En direct de Jonquière, Sébastien, Nicolas et Isabelle continuent leur série d'épisodes sur l'ostéoporose. Dans cette deuxième partie, on aborde le calcium, la vitamine D ainsi que les différentes options pharmacologiques dans le traitement de l'ostéoporose.
Les objectifs pour cet épisode sont les suivants:
Ressources pertinentes en lien avec l'épisode
Qaseem A et coll; Clinical Guidelines Committee of the American College of Physicians. Pharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults: A Living Clinical Guideline From the American College of Physicians. Ann Intern Med. 2023;176:224-38.
Bolland MJ et coll. Calcium intake and risk of fracture: systematic review. BMJ. 2015;351:h4580.
Avenell A, Mak JC, O'Connell D. Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men. Cochrane Database Syst Rev. 2014;2014:CD000227.
Moe S, Paige A, Allan GM. Osteoporosis in postmenopausal women. Can Fam Physician. 2021;67:346.
Nayak S, Greenspan SL. Osteoporosis Treatment Efficacy for Men: A Systematic Review and Meta-Analysis. J Am Geriatr Soc. 2017;65:490-95.
National Institute for Health and Care Excellence (NICE). Osteoporosis: assessing the risk of fragility fracture. London; 2017.
Papaioannou A et coll. 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary. CMAJ. 2010;182:1864-73.
Management of Osteoporosis in Postmenopausal Women: The 2021 Position Statement of The North American Menopause Society'' Editorial Panel. Management of osteoporosis in postmenopausal women: the 2021 position statement of The North American Menopause Society. Menopause. 2021;28:973-97.
Calculateur FRAX Centre for Metabolic Bone Diseases. FRAX: Fracture Risk Assessment Tool. University of Sheffield, UK.
Outil d'aide à la décision Mayo Foundation for Medical Education and Research. Bone Health Choice Decision Aid. Mayo Clinic, USA.
Un nouvel épisode du Pharmascope est maintenant disponible! Dans de ce 113ème épisode, Sébastien, Nicolas et Isabelle débutent une série d'épisodes sur l'ostéoporose. Dans ce premier épisode, on aborde le dépistage, l'évaluation et le diagnostic de l'ostéoporose, une maladie qui n'en est peut-être pas vraiment une…
Les objectifs pour cet épisode sont les suivants:
Ressources pertinentes en lien avec l'épisode
National Institute for Health and Care Excellence (NICE). Osteoporosis: assessing the risk of fragility fracture. London; 2017.
US Preventive Services Task Force. Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement. JAMA. 2018;319:2521-31.
Viswanathan M et coll. Screening to Prevent Osteoporotic Fractures: An Evidence Review for the U.S. Preventive Services Task Force. Rockville (MD): Agency for Healthcare Research and Quality (US); 2018. (Evidence Synthesis, No. 162.
Papaioannou A et coll. 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary. CMAJ. 2010;182:1864-73.
Korownyk C, McCormack J, Allan GM. Who should receive bone mineral density testing? Can Fam Physician. 2015;61:612.
Choisir avec soin. L'ostéodensitométrie. Canada.
Management of Osteoporosis in Postmenopausal Women: The 2021 Position Statement of The North American Menopause Society'' Editorial Panel. Management of osteoporosis in postmenopausal women: the 2021 position statement of The North American Menopause Society. Menopause. 2021;28:973-97.
Calculateur FRAX Centre for Metabolic Bone Diseases. FRAX: Fracture Risk Assessment Tool. University of Sheffield, UK.
Un nouvel épisode du Pharmascope est maintenant disponible! Dans de ce 111ème épisode, Sébastien, Nicolas et Isabelle terminent leur série sur le processus de décision partagée, cette fois en discutant des avantages, des obstacles et des moyens de l'appliquer au quotidien à l'aide d'outils.
Les objectifs pour les épisodes 110 et 111 sont les suivants:
Ressources pertinentes en lien avec l'épisode
Stacey D et coll. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev. 2017;4:CD001431.
Coronado-Vázquez V et coll. Interventions to facilitate shared decision-making using decision aids with patients in Primary Health Care: A systematic review. Medicine (Baltimore). 2020;99:e21389.
Outils d'aide à la décision partagée McCormack J, Pfiffner P. The absolute CVD Risk / Benefit Calculator. 2017.
PEER. Comparing Treatment Options for Pain: The C-TOP Tool.
Mayo Foundation for Medical Education and Research. Bone Health Choice Decision Aid. 2023.
BMJ Publishing Group. BMJ Rapid Recommendations. 2023.
The Ottawa Hospital Research Institute. Patient Decision Aids. 2022.
Primary Health Tasmania. Medication Management – deprescribing. 2023.
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