This podcast was born out of a deep need to more fully understand what was happening to our lives, in our country and around the world, during a time of great uncertainty and instability. But now it feels like we, in the United States, may finally be turning a corner. CNN Chief Medical Correspondent Dr. Sanjay Gupta says goodbye to the podcast he’s hosted for 14 months and almost 300 episodes, and introduces us to a new series for the next chapter in this pandemic.

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When we look back on this pandemic, who and what will we remember? Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is at the top of that list for many. CNN Chief Medical Correspondent Dr. Sanjay Gupta talks to Dr. Fauci about the past year-plus of non-stop press conferences and media appearances, and about what comes next.

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Covid-19 outbreaks have ripped through America’s correctional facilities, but access to the vaccines inside prisons and jails still varies state by state. On today’s episode, CNN’s Chief Medical Correspondent Dr. Sanjay Gupta speaks with Dr. Zachary Rosner about current vaccination efforts in New York City’s correctional system and why it’s so important to get this high-risk population vaccinated.  

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India is fighting a devastating second wave of Covid-19 that has ravaged communities and hospitals across the country. In today’s episode, Dr. Sanjay Gupta explains what went wrong and why it matters to everyone worldwide.

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Pandemics and apocalyptic diseases have long fascinated both writers and readers, but will we want to read about living through Covid-19? CNN Chief Medical Correspondent Dr. Sanjay Gupta hears from writers and industry experts about the past and future of pandemics in fiction.

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Filmmaker Tyler Perry is receiving an honorary Academy Award this weekend, so for today’s podcast, we revisit a conversation between CNN’s Chief Medical Correspondent Dr. Sanjay Gupta and Perry about the quarantine bubble he set up at his studio in Atlanta last summer. They talk about how Perry built his bubble and successfully restarted production without any positive Covid-19 cases on set, and what the experience was like on the inside. 

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Shifts in our behavior during the pandemic have impacted the planet, but will these changes last? On this Earth Day, CNN climate reporter Drew Kann talks with Kim Cobb, a climate scientist at Georgia Tech, about the connection between Covid-19 and climate change, and how we can keep up our green habits even after the pandemic is over. 

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Immunologist Akiko Iwasaki has gained a huge online following during the pandemic for tweeting out explainers of the latest Covid-19 research, as well as calling out sexism in science. CNN’s Chief Medical Correspondent Dr. Sanjay Gupta talks with Professor Iwasaki about treating Covid long-haulers and what we can do to help women and minorities succeed after an incredibly difficult year. 

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At the end of 2020, the vaccine rollout was chaotic: appointments were hard to schedule, vaccine supplies were tight, and the U.S. had administered fewer than 3 million doses over several weeks. But today, things have dramatically improved. CNN’s Chief Medical Correspondent Dr. Sanjay Gupta speaks with Claire Hannan, Executive Director of the Association of Immunization Managers, about how the U.S. turned its vaccine rollout around.

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There are still several countries that have no access to Covid-19 vaccines. CNN reporter Melissa Mahtani shares her opinion about global inequities in vaccine distribution, and how they have impacted her family and her own feelings about getting the vaccine.

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