The C.D.C. recommends against traveling for Thanksgiving, as infection rates are on the rise nationwide. But the airline industry is still expecting a surge in people flying, and scientists have found that air travel is relatively low risk. CNN Chief Medical Correspondent Dr. Sanjay Gupta takes his first flight since March, and CNN correspondent Pete Muntean talks through ways to keep safe on a plane. 

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CNN Senior Writer Thomas Lake tells the story of a pastor in small-town South Carolina who’s doing what he can to minister to his flock. Among his responsibilities, honoring those who’ve died from Covid-19 — even as he tries to avoid becoming one of them. 

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There is promising data from two drug companies with vaccines in the works, but what comes next? One way of speeding the process is an Emergency Use Authorization. CNN Chief Medical Correspondent Dr. Sanjay Gupta talks to the Yale School of Public Health’s Jason Schwartz about EUAs and their role in this pandemic.

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With promising data coming out of multiple trials, the country is now looking at how to distribute a potential Covid-19 vaccine to the public. But who will get it first? CNN’s Chief Medical Correspondent Dr. Sanjay Gupta speaks with bioethicist Art Caplan about the many decisions that must be made before sending any vaccine throughout the country and around the world.

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Several vaccine companies have announced promising early evidence that their vaccines are effective at preventing symptoms of a coronavirus infection. So what comes next? CNN Chief Medical Correspondent Dr. Sanjay Gupta talks to vaccine creator and virology and immunology expert, Dr. Paul Offit about what it takes to get an idea for a vaccine from in the lab into the bodies of people around the world. 

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The U.S. is setting devastating new records nine months into this pandemic. CNN Chief Medical Correspondent Dr. Sanjay Gupta answers listener questions amidst this time of growing uncertainty. 

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Almost a quarter of a million people have died of Covid-19 in the United States. The country is now seeing record-breaking case numbers. Dr. Sanjay Gupta makes an emotional plea for us to start treating the pandemic like the crisis it is, before it is too late.

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South Dakota has had one of the worst spikes of Covid-19 cases in the country, with the positivity rate now climbing above 50%. And still, the state has never instituted a mask mandate or full lockdown. CNN’s Chief Medical Correspondent Dr. Sanjay Gupta talks to Dr. Tom Dean, a family physician in a rural part of the state, about how his community is grappling with this latest outbreak.

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Why does Covid-19 make some people so much sicker than others? Risk factors and pre-existing conditions are part of it, but could there still be another factor? CNN Chief Medical Correspondent Dr. Sanjay Gupta talks to infectious disease expert Dr. Monica Gandhi about the possible role of viral dose in this pandemic.

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Even before the presidential election was called for the former vice president, Joe Biden promised to take the country’s pandemic response in a dramatically different direction. CNN Chief Medical Correspondent Dr. Sanjay Gupta explores the president-elect's plan, as well as promising recent vaccine news from Pfizer. 

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