Actresses Christina Applegate and Jamie-Lynn Sigler have spent decades in the spotlight, with iconic roles on "Married With Children" and "The Sopranos". They've taken on a different role in recent years as the public faces of multiple sclerosis. Sigler was diagnosed when she was just 20 years old, but didn't publicly share her diagnosis until 2016. Applegate received her diagnosis less than four years ago. The two opened up to Hoda about the pain and triumph that has bonded them. 

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