Sage Steele and Mayim Bialik on mental health, Mayim’s depression, anxiety, and OCD, the importance of understanding and accepting oneself, the importance of self-care and mental well-being, the challenges of parenting in the public eye, Mayim on the importance of fostering independence and resilience, Sage’s parents' interracial marriage and how their courage and love have shaped her values and approach to life, the obstacles in sports journalism, Mayim on starting as a child actor, being judged on your looks as a teenage actor, personal healing practices, and how to stay grounded in this crazy world.

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Bill and Sandra on how Bill asked her out at Catch a Rising Star comedy club in New York, Sandra’s avant-garde image, her one-woman shows, her role in "The King of Comedy." Personal anecdotes and experiences, Sandra's Playboy cover in 1992, Bill’s mentions his early attempts to write jokes for various shows and magazines, the lack of depth and authenticity of today's celebrity culture, how to keep a relationship fresh, Sandra’s estranged father, the challenges of being funny in a politically correct environment. Sandra’s critique of Netanyahu and his impact on Israel, Bill’s sleep wear, Sandra’s firing by Woody Allen, and the “what if” had they ever gotten together.

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Bill Maher and Steven Van Zandt on their mutual efforts to stay in shape, Steven’s authentic style, the evolution from tour buses to planes, the changes in Las Vegas from the mob era to corporate, the commercialization of everything, how Steven is a "law and order liberal," police reform, homelessness, and the balance between liberal and woke ideologies, how this conversation is NOT about Bruce Springsteen, accurately depicting stand-up and music in movies, Steven’s role in "The Sopranos," climate change, and Elon and the feasibility of Mars as a habitat. 

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Sage Steele and Sharon Osbourne on the political divide, crime in L.A. vs. everywhere else, the loss of common decency, respect, and the principles of debate, Sharon’s turnaround on therapy, Sage speaking out against Disney, Sharon and the after-effects of Ozempic, Sharon’s challenging relationship with her father, and Sharon’s mission in life to help those who live in fear, her husband’s health, and much, much more. 

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Bill Maher and Bill Burr on why Bill directed Old Dads, the state of cancel culture, what happens if you keep drinking with age, how kids are a buzzkill, the problem with self-driving cars, the age gap between the two Bills, big roast energy, what happened to Bill Maher while wearing leopard shoes, the randomness of award shows, how Bill Burr fell in love with his wife, Bill’s Burr’s take on The Beatles, Bill Burr’s hilarious hometown friends, why war is legal and much, much more. 

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Sage Steele and RFK JR. on his true stance on reproductive rights, why he hasn’t been given a Secret Service detail, his plan for the border, the morality of the current war, controlling A.I., the moment Bobby realized he was a Kennedy, how his life changed when he was fourteen, what makes an addict, his life changing arrest, his quest for love, the epidemic of children with chronic disease, and much much more.

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Bill Maher and Jerry Seinfeld on the gift Bill gave Jerry, Jerry’s attention to detail, the car Jerry picked up Bill in for Comedians in Cars, their respective career maturity, the mistakes Bill made with stand-up crowds, Lorne Michaels’ philosophy on retirement, Bill’s changing desires about performing live, the ruthless nature of Johnny Carson, picking apart compliments, whether there is such a thing as a bad crowd, the genius of Marcus Aurelius, and so much more. 

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Sage Steele and RFK running mate Nicole Shanahan on how Nicole was chosen by RFK to run with him, how a third party candidate is NOT a spoiler, Nicole’s commitment to service not celebrity, the DNC roadblocks to third party candidates, balancing being a mom with running a campaign, Nicole’s A.I. company, her journey from growing up poor to where she is today, how Nicole gained strength from her father’s mental health struggles, the good and the bad of certain social justice movements, the after effects of the lockdowns on the American population, US proxy wars, the hot button issue of politicizing women’s reproductive rights, and much, much more!

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