Dr. Stacy Sims, MSC, PHD, is a forward-thinking international exercise physiologist and nutrition scientist who aims to revolutionize exercise nutrition and performance for women. She has directed research programs at Stanford, AUT University, and the University of Waikato, focusing on female athlete health and performance and pushing the dogma to improve research on all women. She is the author of the book ROAR, written to explain sex differences in training and nutrition across the lifespan. This book challenges the dogma for women in exercise, nutrition, and health and this paradigm shift is the focus of her famous TED Talk "Women Are Not Small Men". Her latest book is called Next Level and is focused on crushing goals through menopause and beyond. Dr. Sims has published over 100 peer-reviewed papers and several books and is a regularly featured speaker at professional and academic conferences.

The lack of research on women's performance and nutrition has negatively affected women's health for generations, but Stacy is on a mission to change that. She and I explore the sex differences in hormones as they relate to performance and how menstrual cycles can be used to a woman's health benefit as an ergogenic aid. She offers recommendations for performance, supplements, nutrition, and recovery in both the follicular luteal phases and highlights the impact of hormonal changes on performance during perimenopause and postmenopause. We touch on supplements, intermittent fasting, and practitioner guidelines for guiding patients through life with confidence in their ability to lift weights, train effectively, and navigate every stage of reproduction with empowering knowledge and confidence.

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

Episode Resources:

Dr. Stacy Sims - https://www.drstacysims.com/

Design for Health Resources:

Designs for Health - https://www.designsforhealth.com/

Designs for Health Practitioner Exclusive Drug Nutrient Depletion and Interaction Checker - https://www.designsforhealth.com/drug-nutrient-interaction/

Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.

https://www.designsforhealth.com/research-and-education/education

Chapters:

00:00 Intro.

04:07 Why has there been so little research on women in the medical field, specifically in nutrition and exercise physiology?

07:00 Implications of the lack of research in women's performance and nutrition.

08:38 Sex differences in hormones as they relate to performance.

13:00 Stacy's ideal research study would be a transdisciplinary effort that incorporates a wide variety of testing for women.

16:20 Menstrual cycles can be used to a woman's health benefit as an ergogenic aid.

20:17 Recommendations for performance, supplements, nutrition, and recovery in the follicular phase.

23:55 Stacy's dietary recommendations for athletes that meet appropriate nutrition for the training.

26:40 Protein and carbohydrate intake guidelines during the luteal phase.

30:01 Current research on oral contraceptives and performance.

33:51 The impact of hormonal changes on performance during perimenopause and postmenopause.

38:45 Heavy weight lifting recommendations for whole life health and performance.

43:39 Training, nutrition, and supplement recommendation differences during perimenopause and menopause.

45:58 Tactics for practitioners to support patients in invoking effective change in sleep hygiene and physical training to increase mobility.

51:15 Creatine and other supplement recommendations for women.

54:30 Iron, estrogen, and testosterone in perimenopausal women.

55:55 Stacy's supplement recommendations include adaptogens based on scientific research.

59:22 Intermittent fasting in women is an easy no for most women.

1:03:33 Stacy's personal daily supplements, favorite health practices, and the ideas she has changed her mind about in recent years.

1:08:05 What Stacy wishes for her daughter as she grows up as an empowered woman.

Dr. Nora Khaldi is a renowned biotech entrepreneur, mathematician, scientist and founder and CEO at Nuritas, an AI-enabled synthetic biology company focused on creating the next generation of intelligent ingredients. Dr. Khaldi is an industry leader in the field of life science, biotechnology and food technology. She holds a Ph.D. in Molecular Evolution, Comparative Genomics and Bioinformatics from Trinity College Ireland and a masters in mathematics from Aix-Marseille University. Her research has focused primarily on research evolution and comparative genomics. Nora holds over 30 patents and is a highly published author.

Together Dr. Khaldi and I dive into the world of peptides and the infinite possibilities of the Nuritas peptide finder. We explore the characteristics of peptides that can change and improve targeted areas, including maintaining muscle health while losing weight, skin health and wrinkles through collagen production and reduced inflammation, and glucose, craving control, sleep promotion, and skin health. Dr. Khaldi reviews the PeptiStrong timeline, highlights targeted populations and shares observations from her personal use. She also addresses the possibilities and concerns associated with AI, reminding us how scientists can enhance their research with its assistance.

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

Episode Resources:

Dr. Nora Khaldi - https://www.nuritas.com/team/dr%E2%81%9Fnora%E2%81%9Fkhaldi/

Design for Health Resources:

Designs for Health - https://www.designsforhealth.com/

Research Blog: Decoding Peptides: The Body's Little Helpers - https://www.casi.org/decoding-peptides-bodys-little-helpers

Research Blog: Bioactive Peptides From the Fava Bean: The Future of Muscular Health? - https://www.casi.org/bioactive-peptides-from-the-fava-bean-future-of-muscular-health

Designs for Health Practitioner Exclusive Drug Nutrient Depletion and Interaction Checker - https://www.designsforhealth.com/drug-nutrient-interaction/

Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.

https://www.designsforhealth.com/research-and-education/education

Chapters:

00:00 Intro.

03:09 Dr. Khali's interest in mathematics and life sciences converged as her career progressed.

5:58 The moment that peptides became the focus of Dr. Khali's research involved wallaby milk.

9:27 Details about peptides and the infinite possibilities of the Nuritas peptide finder.

13:03 The molecular universe of an apple includes more molecular data than all social media put together. Dr. Khali details this library of peptides.

15:44 A timeline of the peptide finder's work and how its inaccuracies are corrected over time to identify solutions.

18:14 Determining which areas to focus on and bring to market starts with securing both health and longevity.

21:16 Pillars in seeking peptides that can change and improve targeted areas, including maintaining muscle health while losing weight.

24:01 Discovering the muscle building mechanisms that became the ingredients in PeptiStrong.

27:51 Why can't humans access all nutrients that are hidden in plants?

31:42 The role of AI in identifying properties and the role of humans in ensuring accuracy.

35:25 Pre-market control testing markers and models and findings from early human clinical trials.

42:18 PeptiStrong timeline and targeted populations and observations from Dr. Khaldi's personal use.

47:15 Designs for Health CEO Amardeep Kahlon's testimonial for performance peptides.

49:15 The combination of mathematics and computer science is AI, and scientists can enhance their research with its assistance.

52:25 PeptiYouth focuses on skin health and wrinkles through collagen production and reduced inflammation.

54:42 Upcoming areas of Nuritas peptide research include glucose, craving control, sleep promotion, and skin health.

58:50 Is it possible that the answers for cancers and other diseases might be found in peptides?

1:01:27 Dr. Nora Khaldi personal favorite supplements, top health practices, and her changing post-pandemic views on remote work.

Dr. Lara Zakaria is an integrative pharmacist, nutritionist, professor, and public health professional specializing in Functional Medicine. A graduate of the Ernest Mario School of Pharmacy, at Rutgers University, she spent 20 years in community pharmacy practice. After developing an interest in nutrition, she earned a MS in Nutrition from the University of Bridgeport and subsequently qualified as a Certified Nutrition Specialist (CNS) as well as an Institute for Functional Medicine Certified Practitioner (IFMCP). Lara currently practices as part of a multi-disciplinary Functional Medicine practice and supervises a professional mentorship program for nutrition and FxMed. Lara is passionate about prevention and reversal of metabolic and autoimmune disease and working with pharmacy professionals to leverage their unique expertise in medication management, drug-drug/drug-nutrient interactions, and genomics to optimize patient medical and nutritional programs.

Together Lara and I discuss the role of the independent pharmacist; drug nutrient interactions and depletions; and Lara's passion about the prevention and reversal of metabolic allergic and autoimmune disease as well as her passion for teaching about the practical application of nutrition and supplements into community pharmacy practice. We explore ideas for providing foundational support for patients, including personalization offerings and consultations; the critical need to evolve and change the way that pharmacy is done while still meeting the needs of patients; and the impressive herbal medicine research findings from a global, cultural and historical perspective that support the work of both pharmacists and functional medicine nutritionists.

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

Episode Resources:

Lara Zakaria - https://larazakaria.com/

Design for Health Resources:

Designs for Health - https://www.designsforhealth.com/

Designs for Health Practitioner Exclusive Drug Nutrient Depletion and Interaction Checker - https://www.designsforhealth.com/drug-nutrient-interaction/

Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.

https://www.designsforhealth.com/research-and-education/education

Chapters:

00:00 Intro

04:15 Lara's transition from major retailer pharmacist to a community pharmacy to functional medicine and nutrition.

09:45 Lara's pharmacy background provides the ideal groundwork for her focus on herbalism and supplements.

13:17 Implementing the practical application of nutrition and supplements in community pharmacy practice.

18:04 Ideas for providing foundational support for patients, including personalization offerings and consultations.

22:27 Generalized billing clarification regarding collaboration.

23:49 Key changes regarding insurance reimbursement with third-party payers.

27:18 The critical need to evolve and change the way that pharmacy is done while still meeting the needs of patients.

28:34 Details of drug nutrient interactions, depletions and supportive interaction checkers.

34:10 Addressing the myths of the supplement industry in favor of being productively critical and supportive of clinically relevant research.

39:01 Herbal medicine research findings from a global, cultural and historical perspective.

44:13 Lara's teaching and volunteer work centers around a holistic and integrative approach to pharmacology.

46:15 Lara's work on the board of the Ocular Wellness and Nutrition Society.

49:01 Connecting with Dr. Lara and resources for pharmacists who want to learn more about functional medicine specific to their profession.

51:42 Lara's personal favorite supplements, top health practices to stay balanced, and the idea that she has changed her mind about in recent years.

Audrey Neff serves as the Director of Marketing for PatientNow, which provides practice management and marketing solutions for over 3,000 aesthetic practices worldwide. Audrey brings over a decade of experience in elective medicine and sales and marketing, seven years of which has been in the healthcare and medical aesthetic verticals. She has a strong passion for helping practices achieve maximum success in their business, and is a frequent industry speaker on practice management and marketing strategy and is faculty for 28 prestigious medical associations and conferences across the U.S.

Together Audrey and I explore the medical aesthetics industry and the growing trend of functional medicine providers offering aesthetics as part of their practices. We discuss the key factors that are driving the exponential growth of the medical aesthetic industry, effective ways to incorporate a supplemental nutrition program into your practice, and how to tailor offerings to meet the needs of both male and female patients, including the language that practitioners want to use – and avoid. The future of the medical aesthetic industry is happening now, and practitioners who are considering taking part in this exciting and growing aspect of whole health will be delighted to learn more about the Designs for Beauty offerings from Designs for Health.

Designs for Beauty

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

Episode Resources:

Audrey Neff - https://www.alkemist.com/about-elan-sudberg/

Design for Health Resources:

Designs for Health - https://www.designsforhealth.com/

Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.

https://www.designsforhealth.com/research-and-education/education

Chapters:

00:00 Intro

03:15 Audrey broke into the medical aesthetic industry at age 22 and quickly excelled with the help of a powerful mentor.

6:16 Key factors that are driving the exponential growth of the medical aesthetic industry.

9:23 Highly effective marketing directed at millennials starts with addressing their 5 core values.

14:10 The importance of practitioners addressing patient values and strategies in their practice efforts.

19:15 The value of before and after photos in establishing client relationships.

20:45 Numbers and growth trends in the medical aesthetic industry, as well as some of the greatest challenges.

27:25 Strategies for making effective supplement and nutrition recommendations and selling value over price.

32:15 Incorporating supplements into a full treatment plan for greater conversion rates.

38:14 The value of offering nutrition protocols in establishing long-term patient loyalty.

40:20 Potential future benefits of offering GLP-1 medicines as a key practice differentiator.

44:54 Tactics for crafting membership models that include contractual commitments and a monthly fee.

49:00 Crafting a tailored offer that is designed to meet the needs of male patients.

50:53 Audrey's career advice to you younger self, the ideas she has changed her mind about, favorite supplements, and top health practices.

Élan M. Sudberg is CEO of Alkemist Labs, a passionately committed contract testing laboratory specializing in plant authentication, botanical ingredient identification and quantitative analytical services to the Food & Beverage, Nutraceutical and Cosmeceutical Industries. He holds a degree in chemistry from California State University Long Beach and has authored numerous journal articles on phytochemistry and analytical techniques for the natural products and nutraceutical industry. He is on the executive committee of the AHPA, as well as AHPA's Education and Research on Botanicals Foundation, and past chair of the Hemp and Medical Marijuana committee. He received the 2019 NutraIngredients-USA NutraChampion award for advocacy of best testing practices.

Together Élan and I explore the supplement industry, from the quality of supplements to the process of testing ingredients. Élan challenges the claim that the supplement industry is untested, unsafe and unregulated, and instead offers insights into what actually happens at each stage of testing and what it really means when raw materials are rejected. He gives an overview of the technology behind DNA testing for specific products, the role of HPTLC testing, commonly adulterated ingredients and the importance of challenging the healthcare and health science industries.

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

Episode Resources:

Élan M. Sudberg - https://www.alkemist.com/about-elan-sudberg/

FDA Dietary Supplement Regulation - https://www.fda.gov/food/dietary-supplements

HPTLC Testing - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658041/

Design for Health Resources:

Designs for Health - https://www.designsforhealth.com/

Designs for Health Quality & Manufacturing - https://www.designsforhealth.com/learn-more/quality-and-manufacturing

Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.

https://www.designsforhealth.com/research-and-education/education

Chapters:

00:00 Intro

03:21 Élan was born into a scientist-filled family, cheated his way through high school chemistry, and now runs the world's biggest small-plant chemistry lab.

6:20 Élan takes on the pervasive myth that the supplement industry is unsafe, unregulated and untested.

09:43 The impact of the Dietary Supplement, Health and Education Act of 1994 (DSHEA).

11:18 Details of the process of each stage of testing for supplemental raw materials.

22:00 A brief but complex history of the technology behind DNA testing for specific products.

28:53 HPTLC testing can distinguish a houseplant from a hot dog, but it can't detect quality.

33:48 Insisting on high quality raw materials- and rejecting some- may or may not mean that suppliers are trying to get away with low quality.

38:48 Commonly adulterated ingredients in the supplement industry including elderberry and ashwagandha.

42:04 Industry trends that are on the rise.

44:15 Élan preferred supplements, personal health practices, and his view on the importance of challenging the healthcare and health science industries.

Jen Donovan is a gut-brain axis specialist who completely rebuilt her life and career as a result of her experience with severe chronic illness. Jen has diverse and comprehensive training including a master's of science in family therapy, a Tension and Trauma Releasing Exercises certification, a Nutritional Therapy Practitioner certification, and a Gut and Psychology Syndrome certification. She is also the author of Rebuild Yourself: Whole Body Practices to Heal Your Brain and Your Nervous System. Through her personal and professional journey, Jen has developed Six Support Protocols to provide a clear, structured, evidence-based, and all-encompassing approach to addressing gut-brain axis neurological issues and finding a thriving life again.

In our conversation, we explore Jen's healing journey from Mast Cell Activation Syndrome, her work with clients on trauma release and nervous system regulation, and how she works with clients with complex chronic illnesses. She shares the series of chronic health challenges that led her to change careers and subsequently prove herself wrong about mental health challenges. She highlights effective nervous system regulation practices, nutrients and supplements that can manage histamine symptoms and nervous system regulation, effective somatic experiencing and shaking exercises, and tactics for practitioners to set realistic timelines that will help patients find success in their healing journey.

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

Episode Resources:

Jen Donovan - https://wholebodyhealingwithjen.com/

Jen's Book - https://www.amazon.com/Rebuild-Yourself-Practices-Nervous-System/dp/B0BRZ1R49C/

Design for Health Resources:

Designs for Health - https://www.designsforhealth.com/

Research Blog: Stinging Nettle: A Potent Herb to Support Immune Health - https://www.casi.org/stinging-nettle-support-immune-health

Nutrition Blog: Clinical Studies Investigate the Role of Lactobacillus and Bifidobacterium in Mood Health - https://www.casi.org/role-of-lactobacillus-and-bifidobacterium-in-mood-health

Research Blog: Spotlight on Benfotiamine - https://www.casi.org/node/640

Science Blog: How the Gut-Brain Axis May Play a Role in Certain Neuropsychiatric Disorders - https://www.casi.org/node/1495

Research Blog: The Relationship Between Histamine Intolerance and Gastrointestinal Health - https://www.casi.org/relationship-between-histamine-intolerance-and-gastrointestinal-health

Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.

https://www.designsforhealth.com/research-and-education/education

Chapters:

00:00 Intro.

03:44 A series of chronic health challenges led Jen to change careers and prove herself wrong about mental health challenges.

05:21 The symptoms that led Jen to a diagnosis and a root cause approach to healing chronic health issues.

09:17 Seeking answers for herself led Jen to the world of natural health options.

12:54 The incorrect association between the physical and mental symptoms of the gut-brain axis and mast cell disorders.

14:32 Although Jen was finding answers, she didn't immediately start implementing new information into her practice.

15:55 Two years of healing included several aspects of natural healing and advanced somatic nervous system regulation techniques.

19:30 Nervous system regulation practices that Jen has implemented into her work with patients, including allowing shaking when the body demands it.

25:47 Shaking exercises for stress management and stimulation of the neurogenic tremor response from the brain stem.

28:55 Somatic experiencing includes much more than simply noticing sounds and colors.

35:32 Jen's dietary recommendations and tactics for empowering patients to stick with a restricted GAPS diet.

42:33 Dietary timelines for adding new foods while balancing the gut microbiome.

47:17 Setting realistic patient expectations for a years-long timeline for healing.

51:19 Jen recommends nutrients and supplements that help manage histamine symptoms and nervous system regulation.

57:50 The importance of building muscle mass and addressing posture in healing.

1:00:00 The structure of Jen's business is designed to meet the needs of every type of patient.

1:02:40 Jen's favorite supplements, top personal well-being practices, and the fad-following ideas she has changed her mind about in her years of practice.

Latisa S. Carson, M.D. is a board-certified physician in Obstetrics and Gynecology and a medical weight loss specialist and is board-certified in Obesity Medicine and is a member of the Obesity Medicine Association. She is the only female African American obstetrician-gynecologist in solo private practice in San Diego County. Her residency training was completed at Southern Illinois University, Springfield, Illinois and her internship year was spent at King/Drew Medical Center in Los Angeles, California. Dr. Carson is a University of Kansas School of Medicine graduate, from Kansas City, Kansas. She has a special interest in helping her community achieve a healthier weight and active lifestyle and offers physicians supervised, medically supported weight loss programs that include nutrition, behavior management, weight loss medication, and exercise guidance.

Together Dr. Carson and I dive into all things weight loss from GLP-1 receptors to the incredibly popular Ozempic and semaglutide compounded medicines. Dr. Carson shares her experience with using GLP-1 receptor antagonists with her patients and offers her wisdom regarding the pillars of health that must be supported by practitioners to optimize lasting patient success. She highlights both the negative and positive side effects associated with weight loss medicines, offers guidelines for effectively tapering off medication, and shares insights into the slow but steady functional medicine changes that are coming into traditional medicine. Her advice is both encouraging and pragmatic, and our conversation is filled with insights for any practitioner who is interested in successfully incorporating today's hottest weight loss medications into their practice.

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

Chapters:

[3:18] Dr. Carson recalls her mother's experience as a nurse, her own introduction to weight loss medicine, and her initial connection with Designs for Health.

[7:20] Defining GLP-1 and GLP-1 receptor agonists and the role of drugs including Ozempic and dual agonist drugs such as Terzepitide in obesity management.

[10:30] Key differences between brand names and semaglutide compounded medicines, as well as injected versus oral medicines.

[14:10] Semaglutide success rates, adherence rates, and average weight loss goal timelines.

[15:15] Dr. Carson's individualized approach to dosing and titration at every stage of a weight loss journey.

[21:30] Dr. Carson's comprehensive support program includes weekly visits, medicines, diet plans, and frequent patient engagement.

[25:35] Muscle mass loss and management of other extreme side effects and complications from these medications.

[33:42] Dr. Carson's experience with favorable side effects in managing other addictions with these medicines.

[36:14] Guidelines for tapering off medication and successfully keeping the weight off.

[39:00] Addressing the mindset of a patient and past trauma in ways that will be most helpful.

[43:25] Dr. Carson shares her desire to integrate functional medicine into her traditional medicine OB practice earlier in her career.

[45:35] Detox pathways are a critical first step to weight loss.

[51:23] Dr. Carson shares what she has changed her mind about over the course of her career, her personal favorite supplements, and her favorite health practices.

Episode Resources:

Dr. Latisa Carson https://www.uniquelyfitmedicalweightloss.com/

Design for Health Resources:

Designs for Health - https://www.designsforhealth.com/

Nutrition Blog: Muscle Tone Matters: The Key to Optimal Body Composition and Metabolic Health - https://www.casi.org/muscle-tone-matters-key-optimal-body-composition-metabolic-health

Nutrition Blog: The Hidden Effects: Medications and Their Impact on Your GI Tract - https://www.casi.org/medications-and-their-impact-on-gi-tract

Research Blog: Influence of Probiotics on Weight Management in Obesity - https://www.casi.org/node/1557

Research Blog: The Stomach-Brain Axis: Hunger's Not All in the Mind - https://www.casi.org/node/971

Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.

https://www.designsforhealth.com/research-and-education/education

Dr. Mark Tager, MD is a speaker and the author of Feed Your Skin Right: Your Personalized Nutrition Plan for Radiant Beauty and is the CEO of San Diego-based ChangeWell Inc. Mark attended Duke University Medical School and trained in family practice at The Oregon Health & Science University. As a physician, he is well-grounded in aesthetic, lifestyle, regenerative, and integrative medicine. Mark founded one of the first integrative medicine centers in the U.S., the Institute of Preventive Medicine, and served as corporate Medical Director for Electro Scientific Industries and as Director of Health Promotion for Kaiser Permanente Oregon. He has been actively involved in training and consulting projects in aesthetics, stem cells, medical malpractice prevention, skin care, and advanced cardiac biomarkers.

Together Dr. Tager and I discuss supplement health for beauty. Patients may come to a practitioner with questions about balancing their hormones, losing weight, or boosting their energy, but almost inevitably they are also interested in optimizing their beauty. Dr. Tager outlines the personalized nutrition questions that practitioners can ask to start the conversation, highlights the essential supplements that can optimize skin health, details the importance of blood flow, Vitamins D, C, and E, and shares insights from simple and powerful skin nutrigenomic testing and SNPs. He also offers clinical pearls regarding collagen and microneedling and shares a wealth of additional supplemental areas for optimizing skin health that can meet the needs of every patient.

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

Chapters:

00:00

01:52 Dr. Mark Tager performs his life's work at the intersection of integrative, functional medicine and aesthetics.

03:50 The four questions behind Dr. Tager's newest book Feed Your Skin Right.

04:50 Personalized nutrition questions that practitioners can ask patients regarding skin health in the realm of functional medicine.

08:54 The key pieces to an optimal diet in maintaining healthy skin including increased Vitamin C and fiber intake.

16:47 Insights from simple and powerful skin nutrigenomic testing and SNPs.

19:15 Shining a light on the effect of dark chocolate on skin health.

20:27 The importance of blood flow to the skin through exercise for optimal health.

23:06 Top supplement recommendations for skin health including bioactive collagen peptides and Omega-3.

28:06 Clinical pearls regarding collagen and microneedling.

30:05 The importance of Vitamin C and Vitamin D in skin health and optimal absorption.

33:01 Mitochondrial health completions and the overlay of drug nutrient completions.

34:10 The simple value of getting enough sleep every night and employing time-restricted eating.

35:00 Two key elements to integrating the Designs for Beauty tools into any practitioner's work.

41:45 Vitamin E is used both topically and orally for skin health and beauty.

43:37 Additional supplemental areas for optimizing skin health including research supporting topical peptides.

48:45 Dr. Mark shares his changed opinion on collagen, his three personal supplements, and his preferred health practices.

Episode Resources:

Dr. Mark Tager - https://www.drtager.com/

Designs for Beauty - https://www.designsforbeauty.com/

Design for Health Resources:

Designs for Health - https://www.designsforhealth.com/

Nutrition Blog: Ten Nutrients to Help Your Skin Glow from the Inside Out - https://www.casi.org/ten-nutrients-help-skin-glow-from-the-inside-out

Research Blog: Summer Glow: Tips to Tone Your Face and Support Skin Health - https://www.casi.org/summer-glow-tips-to-tone-face-support-skin-health

Nutrition Blog: What's Happening on the Outside Could be Caused from Something on the Inside - https://www.casi.org/node/1122

Research Blog: Nitric Oxide – Say Yes to "NO" - https://www.casi.org/node/957

Nutrition Blog: Collagen: A Clinical Look at Hair and Skin Health - https://www.casi.org/collagen-clinical-look-at-hair-and-skin-health

Research Blog: Skin Health: The Benefits of Collagen Peptides - https://www.casi.org/benefits-of-collagen-peptides

Nutrition Blog: Resveratrol to Support Healthy Aging and Skin Elasticity - https://www.casi.org/resveratrol-support-healthy-aging-skin-elasticity

Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.

https://www.designsforhealth.com/research-and-education/education

Dr. Oscar Coetzee has been a pioneer in the field of nutritional science and research for more than 25 years and currently serves as the Senior Director of Clinical Education at Designs for Health. He is an Associate Professor at the Maryland University of Integrative Health, Associate Director of the DHSc program at the University of Bridgeport, and Adjunct Professor at Georgetown Medical School. He is a Certified Board Supervisor for the Certified Nutrition Specialists and is on the National Board Exam Committee for the National Association of Nutrition Professionals. Dr. Coetzee has been on the Designs for Health Scientific Advisory Board since 2016. His professional career began at Fair Oaks Hospital in New Jersey, where he served as a drug counselor, suicide intervention advisor and co-dependency specialist.

In our conversation, return podcast guest Dr. Coetzee brings to light the metabolomic component of GI health and how it relates to mental health conditions including anxiety, depression, and ADHD. He offers insights into the world of psychogenomics, key underrated nutrients that can help with managing anxiety and depression, and the importance of first mastering the circadian rhythm, inflammation, and understanding gene function and expression. Dr. Coetzee shares the one test would run if he only had a few dollars to spend on determining baseline mental health from a functional perspective and reminds listeners of the importance of meeting that standardized baseline before moving to advanced stage interventions.

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

Episode Resources:

Dr. Oscar Coetzee https://naturalhealthcarecenter.com/dr-oscar-coetzee-ph-d-dcn/

Webinar: July 2024 - Sports Performance and Its Association with Psychonutrigenomics - https://www.designsforhealth.com/research-education/library/webinar/sports-performance-and-psychonutrigenomics

Design for Health Resources:

Designs for Health - https://www.designsforhealth.com/

Spotlight Functional Wellness Tests - https://www.designsforhealth.com/spotlight

Science Blog: Recent Review Investigates Association Between Mood Health and Gut Microbiome - https://www.casi.org/review-investigates-association-between-mood-health-gut-microbiome

Lifestyle Blog: Digging a Little Deeper into Depression - https://www.casi.org/digging-a-little-deeper-into-depression-0

Research Blog: The Latest on Vitamin D and Mood Health - https://www.casi.org/vitamin-d-and-mood-health

Research Blog: Supporting Mental Health with Healthy Homocysteine - https://www.casi.org/supporting-mental-health-with-healthy-homocysteine

Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.

https://www.designsforhealth.com/research-and-education/education

Chapters:

00:00 Intro

02:44 The impact of Dr. Coetzee's early work as a drug counselor, suicide intervention advisor and co-dependency specialist on his career.

06:10 The value of leaning into the intersection between psychology, psychiatry and nutrition.

09:39 Psycho-nutrigenomics benefits can be optimized as physicians focus both on the mental and physical health of their patients.

13:05 Key underrated nutrients that can help with managing anxiety and depression.

17:50 A personalized approach to determining deficiencies through bloodwork, blood sugar levels, gut microbiome, inflammation levels, and more.

21:34 Dr. Coetzee shares memorable experiences with tackling patient thyroid levels, psychobiotics, and anemia.

24:47 Gene function, SNPs, and genetic expression when assessing B vitamins for optimal mental health.

31:06 Anxiety and depression — the circadian rhythm, inflammation and LPS, and the Brain-derived Neurotrophic Factor.

37:28 Does inflammation cause anxiety and depression or does anxiety and depression cause increased inflammation?

42:25 The importance of meeting a standardized baseline before moving to advanced stage interventions.

45:02 Conquering the circadian rhythm piece of anxiety and depression with psychobiotics.

48:46 Determining how and when to work with neurotransmitters when approaching ADHD.

54:15 Dr. Coetzee's aggressive approach to dosing when oversaturation is needed.

58:33 If Dr. Coetzee could spend his money on any design related to mental health, this is where he would focus his efforts.

01:01:11 Sporebiotics as they relate to intestinal permeability and psychobiotics as they support brain health.

Dr. DJ Sims is a Naturopathic Doctor, published author, and prolific speaker. She received her Bachelor's in Biology from Prairie View A&M University, in Texas and completed her doctorate at Sonoran University of Health Sciences in Phoenix (formerly SCNM). She has served as an Assistant Professor and Core Faculty at Bastyr University California and was a former Adjunct Professor at SCNM in Arizona. ​Dr. DJ established the virtual clinic Superhero Skin+Care to remind women of their identity and bring out the adventurous, gorgeous superhero within them. To do this, she provides personalized treatment plans to improve the skin, reset the liver, and support digestion. Dr. DJ is a leader in naturopathic dermatology and a renowned keynote speaker who makes complex medical information accessible and entertaining.

Together Dr. Sims and I talk about conquering acne, eczema, psoriasis, and hair loss. She highlights her approach to uncovering the root causes of common dermatological ailments, general diet, and supplemental recommendations for treating microbiome and food sensitivities, and shares clinical pearls regarding accessibility and affordability of skin healthcare. Dr. DJ talks about the value of supplements including Vitamin A and zinc when combating the dysbiosis that can cause acne, key differences in the topical skin barrier, dysbiosis and stress that can all lead to eczema, and the potential causes and nutritional and lifestyle analysis for treating hair loss. Dr. DJ is working to not only treat her patient's skin but to unleash their inner superhero and restore the confidence that comes with having clear skin.

I'm your host, Evelyne Lambrecht, thank you for designing a well world with us.

Key Takeaways:

[2:00] Dr. DJ Sims makes complex naturopathic dermatology and other complex medical information accessible and entertaining, even at Comic-Con.

[4:14] The role and encouragement that Dr. DJ's parents offered as she entered the world of naturopathic medicine, and the patients that first inspired her to continue her work.

[8:52] A high-level overview of Dr. DJ's approach to uncovering the root causes of common dermatological ailments.

[10:38] Top root causes of acne including hormonal imbalance of androgen or cortisol excess, dysbiosis or loss of good bacteria, and food sensitivities.

[12:05] Liver enzymes, genetic testing, and the need for higher liver support.

[13:05] Dr. DJ's preferred method for hormone testing is DUTCH testing, which offers diet, lifestyle, and hormone answers.

[16:35] General diet and supplemental recommendations for treating microbiome and food sensitivities.

[20:10] Dr. DJ's timeline to gut treatment, including healing and killing.

[21:55] Clinical pearls regarding GI Revive and L glutamine and accessibility and affordability of skin healthcare.

[24:44] The value of Vitamin A and zinc when combating the dysbiosis that can cause acne.

[29:10] Dosing recommendations for Vitamin A and zinc supplements.

[33:37] Addressing the skin microbiome, dietary concerns, and food sensitivities.

[39:46] Key differences in the topical skin barrier, dysbiosis, and stress can all lead to eczema.

[45:55] Addressing the depression and anxiety that accompanies acne and other skin issues.

[47:40] Psoriasis is often a grab bag of symptoms that acts like eczema but has its own unique sensitivities as well.

[49:50] Causes and nutritional and lifestyle analysis for treating hair loss, including biotin and amino acids.

[59:28] Dr. DJ shares what she has changed her mind about in her years of practice, her three favorite supplements, and essential health practices.

Episode Resources:

Dr. DJ Sims

Eye of Newt and Wool of Bat: The Science Behind Magic Potions and Spells | Comic Con@Home 2020

Design for Health Resources:

Designs for Health

Nutrition Blog: Ten Nutrients to Help Your Skin Glow from the Inside Out

Research Blog: Vitamin A & Retinoids for Skin Health

Research Blog: Skin Health: The Benefits of Collagen Peptides

Blog: Summer Glow: Tips to Tone Your Face and Support Skin Health

Blog: Dealing with Eczema at the Source: Autoimmunity

Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.