Part 4 of 4: My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide.Â
Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups.
In this episode, you’ll hear about:- How a Thanksgiving article about Dr. Sam Gambhir inspired the founding of Earli
- Earli’s groundbreaking approach to revolutionizing cancer detection using synthetic biology
- The challenges of translating scientific discoveries into real-world clinical applications
- Overcoming obstacles and achieving breakthroughs in diagnostics and therapeutics
- Cyriac’s unwavering commitment to transforming cancer into a manageable condition
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Find Our Guest, Cyriac Roeding, at these links:Â https://www.linkedin.com/in/cyriacroeding/https://www.earli.com/Â https://www.joinrewind.com/Â
Find Our Host, Jon Chee, at these links:Â https://www.linkedin.com/in/joncheehttps://www.excedr.com
Excedr Socials & WebsiteLinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/Â
Enriched Notes:Topics Mentioned:Earli: https://www.earli.com/Â Stanford University: https://www.stanford.edu/Andreessen Horowitz: https://a16z.com/Marc Benioff: https://www.linkedin.com/in/marcbenioff/Khosla Ventures: https://www.khoslaventures.com/Lab Equipment List, Synthetic Biology Research: https://www.excedr.com/blog/lab-equipment-list-for-synthetic-biology-researchHow to Bootstrap Your Biotech Startup & Scale: https://www.excedr.com/resources/how-to-bootstrap-biotech-startupWhen & How to Pivot a Biotech Startup: https://www.excedr.com/blog/when-how-to-pivot-a-biotech-startupHow to Craft a Pitch Deck for Biotech Investors: https://www.excedr.com/resources/how-to-craft-a-pitch-deck-for-biotech-investorsTop VC Firms for Biotech in 2024: https://www.excedr.com/blog/top-vc-firms-for-biotechBiotech Startup Support Resources: https://www.excedr.com/resources-category/biotech-startup-support
People Mentioned:Dr. Sam Gambhir: https://en.wikipedia.org/wiki/Sanjiv_Sam_GambhirDavid Suhy: https://www.linkedin.com/in/davidsuhy/Jorge Conde: https://www.linkedin.com/in/jorge-conde-4099225/Jim Allison: https://faculty.mdanderson.org/profiles/james_allison.htmlPam Sharma: https://faculty.mdanderson.org/profiles/padmanee_sharma.htmlPhil Greenberg: https://www.fredhutch.org/en/faculty-lab-directory/greenberg-philip.html
Timestamps:00:00 Intro02:08 How a Thanksgiving article about Dr. Sam Gambhir inspired Earli’s founding05:43 Meeting Dr. Gambhir and learning biology as a non-scientist entrepreneur09:02 Discovering the “one idea” that led to Earli’s revolutionary synthetic biology approach12:54 Earli’s mission to transform cancer detection and diagnostics17:30 Overcoming major challenges and achieving breakthroughs in diagnostics accuracy21:54 The emotional and scientific legacy of Dr. Gambhir and its impact on Earli’s vision26:28 Earli’s innovative approach to bridging diagnostics and therapeutics30:05 The business potential of Earli’s platform for cancer and other diseases33:04 Cyriac’s advice on taking the road less traveled as an entrepreneur35:41 OutroThe Biotech Startups Podcast gives you a front-row seat to the business
and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.
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