DrBeen#24 How to Maximize Autophagy

When Does Autophagy Begin In Our Body? This question is most asked, and this topic is very researched. Let's review what we know so far.

Dr. Ana Maria Cuervo, MD, Ph.D notes that macroautophagy starts within 30 minutes to an hour of starvation. When do we starve? In the intermittent fasting of 8-16. The macroautophagy starts within 8 hours if there are no snacks. The chaperon mediated autophagy occurs during the 16 hours. If you keep the 16 hours window including the sleep then the neurons are able to perform autophagy as well.

DrBeen: Medical Education Online
https://www.drbeen.com/

FLCCC | Front Line COVID-19 Critical Care Alliance
https://covid19criticalcare.com/

URL list from Thursday, Sep. 1 2022

Yoshinori Ohsumi - Wikipedia
https://en.wikipedia.org/wiki/Yoshinori_Ohsumi

HOW LONG Does It Takes To Activate AUTOPHAGY? | Dr Ana Maria Cuervo Interview Clips - YouTube
https://www.youtube.com/watch?v=D6QcE3wVQ14

Short-term fasting induces profound neuronal autophagy - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106288/

Autophagy: Definition, Process, Fasting & Signs
https://my.clevelandclinic.org/health/articles/24058-autophagy

6 Signs And Symptoms of Autophagy
https://www.healthline.com/nutrition/signs-of-autophagy#5.-Weight-loss

How Long do You Have to Fast for Autophagy? – spermidineLIFE® US
https://spermidinelife.us/blogs/news/how-long-do-you-have-to-fast-for-autophagy#:~:text=Studies%20have%20shown%20that%20autophagy,humans%20but%20can%20be%20possible.

How Long Do You Need to Fast for Autophagy?
https://www.medicinenet.com/how_long_do_you_need_to_fast_for_autophagy/article.htm

Ana Maria Cuervo, M.D., Ph.D. | Faculty Directory | Albert Einstein College of Medicine
https://www.einsteinmed.edu/faculty/8784/ana-maria-cuervo/

Cuervo AM - Search Results - PubMed
https://pubmed.ncbi.nlm.nih.gov/?term=Cuervo%20AM

The coming of age of chaperone-mediated autophagy - PubMed
https://pubmed.ncbi.nlm.nih.gov/29626215/

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835977/

How to control self-digestion: transcriptional, post-transcriptional, and post-translational regulation of autophagy - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441840/

Chaperone-mediated autophagy sustains haematopoietic stem-cell function - PubMed
https://pubmed.ncbi.nlm.nih.gov/33442062/

Molecular definitions of autophagy and related processes - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494474/

The different autophagy degradation pathways and neurodegeneration - PubMed
https://pubmed.ncbi.nlm.nih.gov/35134347/

How Long Do You Need to Fast for Autophagy?
https://www.medicinenet.com/how_long_do_you_need_to_fast_for_autophagy/article.htm#:~:text=Autophagy%20is%20believed%20to%20begin,around%2048%20hours%20of%20fasting.

Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials | Cardiology | JAMA Network Open | JAMA Network
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2787246?resultClick=1

ADULT NEUROGENESIS IN HUMANS: A Review of Basic Concepts, History, Current Research, and Clinical Implications - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659986/#:~:text=Neurogenesis%20is%20the%20formation%20of,the%20hippocampus%20(Figure%201).

Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.

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