The third in a series about the beneficial effects of Ashwagandha, this episode looks at the anti-stress and adaptogenic effects of this incredible herb. Ashwagandha helps improve neuronal plasticity and regeneration, and reduces the damage and death of these cells. To accomplish this effect, ashwagandha triggers the upregulation of HSP70 proteins. Let's review.

URL list from August 3, 2023

Pharmaceutics | Free Full-Text | Ashwagandha (Withania somnifera)—Current Research on the Health-Promoting Activities: A Narrative Review

https://www.mdpi.com/1999-4923/15/4/1057

Evidence-Based Efficacy of Adaptogens in Fatigue, and Molecular M...: Ingenta Connect

https://www.ingentaconnect.com/content/ben/ccp/2009/00000004/00000003/art00004

Heat Shock Protein 70 (Hsp70) as an Emerging Drug Target - PMC

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895966/#:~:text=Heat%20shock%20protein%2070%20(Hsp70)%20is%20a%20molecular%20chaperone%20that,or%20aggregation%20until%20conditions%20improve

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Adaptogenic activity of Withania somnifera: an experimental study using a rat model of chronic stress - ScienceDirect

https://www.sciencedirect.com/science/article/abs/pii/S0091305703001102

Phytotherapy Research | Medicinal Chemistry Journal | Wiley Online Library

https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.858

Frontiers | c-Jun N-terminal Kinase (JNK) Signaling as a Therapeutic Target for Alzheimer’s Disease

https://www.frontiersin.org/articles/10.3389/fphar.2015.00321/full

Frontiers | DAF-16/FOXO Transcription Factor in Aging and Longevity

https://www.frontiersin.org/articles/10.3389/fphar.2017.00548/full

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