In this engaging interview, we ask Dr. Nora Volkow what common misconceptions exist that can influence the way clinicians treat pain and manage opioid addiction. We also ask her what risk factors are associated with opioid addiction and what early warning signs exist that a patient is becoming addicted. She also shares with us the most effective pain biomarkers available today, and in development so that we may be able to more effectively manage pain and avoid some of the risk associated with opioid treatment for pain.