Dr. Richard Cathomas, medical oncologist from Zurich in Switzerland discusses Immunotherapy in muscle-invasive bladder cancer.

He goes into the mechanism of action of immunotherapy and why could it work well in bladder cancer. 
Where do we currently stand with the use of immunotherapy in the NEOADJUVANT setting of muscle invasive bladder cancer? And what is currently the best place to integrate immunotherapy for METASTATIC bladder cancer?

Prof. Dr.  Cathomas closes with the answer to the question of why some patients benefit much more than others from immunotherapy. 

Prof. Dr. Richard Cathomas is oncologist panel member on the EAU Guidelines for muscle-invasive bladder cancer.

In this second edition of two updates, Professor Nicolas Mottet, the chair of the EAU Guidelines panel for prostate cancer, discusses which are the most important changes and new recommendations in the new EAU Guidelines for prostate cancer for 2022 relating to treatment approaches.

In this first edition of two updates, Professor Nicolas Mottet, the chair of the EAU Guidelines panel for prostate cancer, highlights the work of the panel.
His talk includes new systematic reviews, and outlines which are the most important changes in the new EAU Guidelines for prostate cancer for 2022 relating to the definition of clinically localized and clinically significant prostate cancer, diagnostic evaluation, particularly transperineal biopsy. Professor Nicolas Mottet also discusses key points relating to staging and imaging.

What exactly is pain? What do I have to know about pain if I am treating patients with chronic pelvic pain? What is necessary to diagnose a chronic pelvic pain syndrome? What factors are key to successfully treat patients with a chronic pelvic pain syndrome? And what are the psychological aspects of chronic pain? Prof Daniel Engeler answers these questions.

Prof Engeler is chairman of the EAU Guidelines panel on Chronic Pelvic Pain.

Dr Bela Köves answers questions about the changes in the guidelines chapter of recurrent urinary tract infections. And in particular, he elaborates on the question, what  the most important updates are for the specific preventive approaches. Are there any changes regarding lifestyle advices or behavioral modifications? 

The second part of the podcast covers the updates about the use of topical oestrogen, immunoactive prophylaxis, the changes about prophylaxis with probiotics and cranberries. 

Dr Bela Köves is a member of the EAU Guidelines panel on urological infections. 

In this edition, we have Professor Berk Burgu, a member of the EAU Guidelines panel for Paediatric Urology, discussing vesico-ureteral reflux in children, including its diagnosis and treatment. 

We get answers to the question what is vesico-ureteral reflux is and Prof. Burgu explains the importance.  Should we treat vesico-ureteral reflux immediately after being diagnosed? Is there a structured diagnostic work-up for vesico-ureteral reflux? 

In the last part of the podcast, Prof. Burgu discusses the options for the surgical treatment of reflux. 

In this edition, we have Dr. Toine van der Heijden discussing the three different diversions mentioned in the guideline after cystectomy - uretero cutaneostomy, ileal conduit and an orthotopic neobladder – along with the reasons for choosing a certain diversion and helping the patient to decide.

Dr. Toine van der Heijden is a member of the EAU Guidelines panel for Muscle Invasive Bladder Cancer.

The new guidelines on Non-neurogenic Female LUTS have replaced the old Urinary Incontinence Guideline. Dr. Arjun Nambiar discusses the thought process behind this and tells what's new. He also goes deeper into the process that guidelines users or readers may not be aware of.

Dr. Arjun Nambiar is member of the EAU Guidelines panel for non-neurogenic Female LUTS.

Dr. Sachin Malde catches up with us about the current status and future challenges in minimally invasive treatments for BPO. He elaborates on the surgical options and the EAU guidelines recommendations about the newer surgical treatments for BPO.

We also gain insight into the criteria the guidelines panel use to make a recommendation about a particular treatment. And finally, Dr. Malde discuss the future developments that he think will help to strengthen the recommendations made by the EAU guidelines in this area.

Dr. Sachin Malde is an associate member of the EAU Guidelines panel on Management of Non-neurogenic Male LUTS.

How can we improve the organ pool for kidney transplantation and how do we implement all alternatives in the current transplant teams? 

Dr. Oscar Rodriguez Faba is an associate member of the EAU Guidelines panel for kidney transplantation and talks about these questions in this podcast.

Oscar Rodriguez Faba closes with the answer to the question if the results are comparable to cadaveric donors and conventional living donors.