Kicking off season 3 of Endocrine Feedback Loop, host Chase Hendrickson, MD, from Vanderbuilt University Medical Center discusses a recent article with two pediatric endocrinologists: Marcela Vargas Trujillo, MD, from the University of California, San Diego, and Rady Children’s Hospital and Selma Witchel, MD, from the University of Pittsburgh Medical Center Children’s Hospital of Pittsburgh. They discuss an article from The Journal of Clinical Endocrinology & Metabolism: “Optimizing the Timing of Highest Hydrocortisone Dose in Children and Adolescents with 21-Hydroxylase Deficiency.” For more information, including helpful links and other episodes, visit our website at https://www.endocrine.org/journals/endocrine-feedback-loop-podcast-series