In this episode, host Dr. Jose Silva and Dr. Padraic O’Malley, a urologic oncologist from University of Florida Health, discuss how to diagnose and treat upper tract urothelial carcinoma.

Referencing official guidelines and personal experiences, the doctors discuss various treatments such as tumor ablation, JELMYTO, neoadjuvant chemotherapy, and nephroureterectomy. They also discuss the role of lymph node dissection and the significance of Lynch syndrome. Additionally, they touch upon the Thulium laser and updated staging guidelines. The episode concludes with discussions about follow-up care, and the doctors agree on the need for a standardized reporting system and risk stratification guidelines for improved patient management.

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SHOW NOTES

00:00 - Introduction

02:09 - Initial Presentation of Patients with Upper Tract Urothelial Carcinoma

10:54 - Discussion on Lynch Syndrome

14:27 - Risk Stratification in Patients

15:37 - Tumor Ablation and Intracavitary Therapies

26:47 - The Use of Thulium Laser in Treatment

28:50 - Discussion on High Volume Disease

32:39 - Discussion on High Grade Tumors

38:23 - The Role of Neoadjuvant Chemotherapy

43:02 - Post-Treatment Follow Up

45:18 - Standardized Reporting in Guidelines