Jerry Rosenbaum is a psychiatrist, a world-renowned expert on mood and anxiety disorders, and the director of the Center for the Neuroscience of Psychedelics at Massachusetts General Hospital in Boston. He was the Stanley Cobb Professor of Psychiatry at Harvard and the Chief of Psychiatry at Mass General for 17 years, from 2002-2019. During our conversation, Jerry talks about his career in psychiatry, the role of rumination in mental illness, the potential for psychedelics to decrease suffering and improve human well-being, and the goals of the Center for the Neuroscience of Psychedelics.

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(00:00) Intro

(02:45) Jerry shares how he got into psychiatry, psychedelics and the role of rumination across mental illnesses

(09:19) Jerry talks about The Default Mode Network of the human brain - people who ruminate are found to be more active in that network.

(11:10) Jerry talks about the potential contributors to psychedelic study

(18:31) Funds and investments to psychedelic study

(24:02) Jerry discusses whether he was satisfied with the options available to help treat his patients in the past

(24:31) What is psychodynamic psychotherapy?

(27:21) Jerry’s thoughts on anti-depressants

(35:17) How does an antidepressant function?

(38:40) About ketamine and ketamine-assisted psychotherapy

(42:03) Jerry shares more about research on psychedelics and the different psychedelics available today

(45:08) Who would benefit the most from research?

(47:39) The controversy in the world around psychedelics

(51:26) What is the appropriate setting for taking psychedelics?

(01:04:53) Where are we right now in terms of the efficacy of psychotherapy and related treatments?

(01:09:09) How can individuals help in studies related to psychotherapy and psychiatry?

(01:12:05) Jerry’s words to people who wish to help or need help right now

(01:15:10) Jerry’s thoughts on accessibility for psychedelic medicines in the future

(01:18:39) Jerry shares how what the treatment experience looks like for individuals