Many people in our community say it has become virtually impossible to shift the weight since cancer and menopause. So of course we ask ourselves: What role do GLP-1 medicines play in cancer survivorship and what do we really know about their safety, risks, and benefits? 

In this episode, I’m joined by Caroline Tweedie, currently working as the lead cancer nurse in the North East of England. With over 17 years’ experience as a Clinical Nurse Breast Specialist, Caroline has dedicated her career to improving the lives of those affected by breast cancer and sits on the NICE committee shaping national breast cancer guidance.

We explore, with curiosity - and never with judgement:

- What GLP-1 medicines are and why they are so effective

- Safety concerns and what the evidence shows for cancer survivors

- Why these drugs matter in breast cancer survivorship

- The role of GLP-1s in weight, muscle, bone health, inflammation, and fatigue

- Natural strategies that may work on similar pathways

- Key risks to be aware of: hair loss, sarcopenia, drug absorption, and endocrine therapy interactions

- What happens when you stop taking the drug

- Practical advice for patients and clinicians navigating this new landscape

Caroline also shares her insights on why weight loss isn’t the same as fitness, why muscle is the “anti-fatigue organ,” and what both patients and healthcare professionals need to know before considering GLP-1 use in survivorship care.

This is a nuanced, evidence-based discussion that puts patients at the centre. Whether you’re a survivor curious about GLP-1s or a healthcare professional supporting patients, this episode offers clarity, compassion, and practical takeaways.

Episode Highlights:

00:00 Intro

12:09 Survivorship Challenges Beyond Cancer Treatment

15:35 Weight Loss Treatments: Risks & Support

16:42 Bariatric Surgery vs Rapid Weight Loss

22:18 Protein Intake for Menopause Health

25:04 "Deciding on GLP1 Treatment"

29:06 GLP-1 Eligibility Criteria Explained

35:40 "Drug Trials and Patient Safety"

42:19 Obesity Support After Cancer

43:31 Diabetes Drugs, Costs, Future Hope

Connect with us:

For more information and resources visit our website: www.menopauseandcancer.org

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Join our Facebook group: www.facebook.com/groups/menopauseandcancerchathub