JAMA Health Forum Editor John Ayanian, MD, MPP, and Associate Editor Julie Donohue, PhD, speak with Aaron S. Kesselheim, MD, JD, MPH, and Genevieve P. Kanter, PhD, about the role of advisory committees convened by the US Food and Drug Administration (FDA) to guide its decisions on whether to approve new prescription drugs. They also consider how the FDA has responded to recommendations from these advisory committees over the past decade. Related Content:

• Association of Advisory Committee Votes With US Food and Drug Administration Decision-Making on Prescription Drugs, 2010-2021
• The Real Question the FDA Is Asking Its Advisory Committees