The Filtrate:

Joel Topf

Swapnil Hiremath

Matt Sparks

Editor:

Joel Topf

Show Notes:

The 2010 RFN Top Nephrology Stories

The 2021 NephJC Top Nephrology Stories

Number 10: AKIKI

AKIKI 2 in The Lancet

AKIKI 2 in NephJC

AKIKI 2 on Freely Filtered

Number 9: Effect of Salt Substitution on Cardiovascular Events and Death

The Salt Substitute and Stroke Study (SSaSS) in the NEJM

The Salt Substitute and Stroke Study (SSaSS) in NephJC

FDA Issues Final Guidance Regarding Use of an Alternate Name for Potassium Chloride in Food Labeling

Number 8: AURORA, voclosporin for Lupus Nephritis

Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1) in the Lancet

AURORA 1 on NephJC

AURORA 1 on Freely Filtered

Number 7: FIGARO trial of finerenone for CV outcomes

Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes in the NEJM

Rates of Hyperkalemia after Publication of the Randomized Aldactone Evaluation Study by David Juurlink

Joel’s intermission

FDA Rejections

Tricida’s Veverimer

Roxadustat

Bardoxolone

Tenapanor

Number 6: Pig Kidney Transplant.

As covered in the New York Times

Clinical Pig Kidney Xenotransplantation: How Close Are We? from JASN

Number 5: KDIGO Blood Pressure Guidelines

KDIGO Guidelines

As discussed in NephJC

And on Freely Filtered

Matt’s article on ACCORD he wrote for RFN as a fellow

Number 4: Chlorthalidone for Hypertension in Advanced Chronic Kidney Disease (CLICK)

CLICK in the NEJM

CLICK on NephJC

CLICK on Freely Filtered

Number 3: Dapagliflozin helps IgA nephropathy

The Lancet

FDA OKs First Proteinuria Drug for IgA Nephropathy: delayed released budesonide

Number 2: New eGFR formulas, now race free.

New Creatinine- and Cystatin C–Based Equations to Estimate GFR without Race in the NEJM

Number 16: Fixing ADPKD in mice

Renal plasticity revealed through reversal of polycystic kidney disease in mice in Nature Genetics

Press release from Yale

Number 1: KDIGO GN Guidelines

PDF in Kidney International

NephJC Discussion

Last Month in Nephrology skeptical of all the Rituximab

Tubular Secretions

Overcooked! All You Can Eat

Lego Porsche 911

Lego Baby Yoda (Grogu)

Beyblades