Last Week in Medicine

Half Dose DOAC for Long Term VTE Prevention, Biomarker Guided Antibiotics for Sepsis, GPT-4 Assistance for Physicians, Optimal Vasopressin Initiation for Shock, DOAC vs No AC for A fib After Intracerebral Hemorrhage, HFNC vs NIV for Respiratory Failure


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For this episode we are joined by EBM guru, Dr. Brian Locke, who deftly breaks down all of our statistics questions. 

Is half dose DOAC as good as full dose DOAC for preventing VTE, and does it reduce bleeding risk? Can procalcitonin reduce duration of antibiotics for infections without compromising mortality rates? Can LLMs like GPT-4 help physicians manage patients better? Can reinforcement learning models predict when to start vasopressin in patients with septic shock? What is the risk of resuming anticoagulation in patients with atrial fibrillation and prior intracerebral hemorrhage? Is high flow nasal cannula as good as non-invasive ventilation for different types of respiratory failure? We answer all these questions and more!

Half Dose DOAC for Long Term VTE Prevention (RENOVE)

Biomarker-Guided Antibiotic Duration (ADAPT-Sepsis)

GPT-4 Assistance for Physician Performance

Optimal Vasopressin Initiation for Septic Shock (OVISS)

DOACs for A fib after ICH (PRESTIGE-AF)

High Flow Nasal Cannula vs NIV for Respiratory Failure (RENOVATE)



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Last Week in MedicineBy Stephen Jenkins, MD, Austin Rupp, MD

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