Dr. Lecia Sequist, an expert in lung cancer and early detection, and Dr. Jeff Yang, a renowned thoracic surgeon, join Chadi to unravel the complexities of early lung cancer detection. Together, they explore the nuances of lung cancer screening, including the challenges of overdiagnosis and managing false-negative and false-positive results. The discussion delves into cutting-edge advancements like multi-cancer early detection tests, current patient screening eligibility criteria, and the critical factors contributing to low screening rates, such as accessibility barriers. They end on a note to raise awareness about the importance of lung cancer screening, emphasizing its safety, simplicity, and potential to save lives.

Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/

Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Maz Jobrani, star standup comedian and actor, joins the show to share his career journey and his beginning as an immigrant turned comedian and celebrity. Maz shares his sister's journey when diagnosed with breast cancer at a very young age. He opens up with details on challenges of being one of her caregivers and how he balanced comedy with tragedy. His sister catalogued her journey in a documentary available on Amazon Prime, titled "Everything Must Change," that is a must-watch. Maz and Chadi celebrate his sister's life and highlight how "The Cancer Journey" addresses all elements pertaining to the unfortunate journey patients and families must undertake.

Find out more about Maz Jobrani.

https://www.mazjobrani.com/

Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/

Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Chadi sits down with Dr. Matt Davids, Director of Clinical Research in the Division of Lymphoma at Dana-Farber Cancer Institute, to unpack the latest breakthroughs in leukemia and chronic lymphocytic leukemia (CLL) from the ASH annual meeting. A pioneer in CLL treatment, Dr. Davids recounts the development of venetoclax, a transformative therapy he helped bring to clinical use over a decade ago, setting the stage for discussions on emerging updates. Together, they explore advancements in BTK inhibitors across three distinct classes, the potential of novel targeted therapies, innovative combination regimens, and the shifting paradigms in treating blood cancers, including a nod to the latest clinical trials of high potential.

Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/

Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

As the holidays approach, questions about maintaining nutrition, wellness, and a healthy lifestyle take center stage. Australian nutrition icons Kim Morrison and Cyndi O'Meara join Chadi to explore vitalistic principles that emphasize natural health approaches without relying on medication. They dive into how the holiday season amplifies mental health and nutritional struggles and share actionable strategies to tackle these challenges beyond mere willpower. With an anthropological lens, they break down how understanding your unique body can guide you to maintain a healthy weight, improve overall health, and develop lasting habits. The conversation also provides practical tips for identifying high-quality ingredients and making mindful food choices that support your wellness goals.

Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/

Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Leading into the ASH Annual Meeting, Dr. Kami Maddocks, professor in the Division of Hematology at The Ohio State University and medical director of infusion services at The James Comprehensive Cancer Center, provides an in-depth analysis of advancements in non-Hodgkin lymphoma care, with a focus on aggressive B-cell lymphoma. She explores the evolving roles of immunotherapies like CAR-T cells and bispecific antibodies in high-risk patient populations, discusses the impact of cell-of-origin testing on frontline treatment decisions, and evaluates the latest data guiding choices between R-CHOP, transplant, and CAR-T therapy after first relapse. Dr. Maddocks also highlights the promise of BTK inhibitors and maintenance approaches in transforming patient outcomes, offering insights into the future of lymphoma treatment.

Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/

Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Dr. Vivek Subbiah returns for another edition of Vivek's Takes, sharing his insights on key updates from ESMO Congress 2024, including breakthroughs in neuroendocrine tumors, gastric cancer, and non-small cell lung cancer. He also delves into the highlights of his AACR debate on integrating early cancer detection with AI, arguing for the transformative potential of humans with AI versus the readiness of AI today.

Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/

Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Chadi welcomes Dr. Andrea Apolo, an internationally recognized leader in bladder cancer research from the National Cancer Institute. Dr. Apolo shares her expertise on recent advancements in urothelial cancer therapy, including key breakthroughs in checkpoint inhibition that have marked a significant turning point in treatment. The conversation delves into optimal sequencing and combination strategies for checkpoint inhibitors, contrasts in treatment approaches between early-stage and late-stage disease, and the evolving landscape of bladder-sparing options. Dr. Apolo also provides an in-depth look at the comprehensive process of designing, executing, and publishing impactful clinical research, highlighted by her latest publication in The New England Journal of Medicine.

Read more about her NEJM trial.

https://www.nejm.org/doi/abs/10.1056/NEJMoa2401726

Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/

Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Dr. Joe Mikhael, Chief Medical Officer of the International Myeloma Foundation (IMF) and Professor at TGen, takes us beyond his medical career to explore the personal experiences that have shaped his journey in oncology. Dr. Mikhael discusses the IMF’s targeted strategies for reducing health disparities among diverse ethnic and racial groups affected by myeloma, shedding light on specific initiatives aimed at improving access and outcomes. He also dives into his role in medical education, where he mentors the next generation of oncologists through innovative fellowship programs, advancing research, and fostering a more inclusive approach to cancer care.

Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/

Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

Tom Beer, Chief Medical Officer of the Multi-Cancer Early Detection (MCED) program at Exact Sciences, delves into the groundbreaking science behind MCED tests, which use advanced biomarkers for early detection of multiple cancer types. He explains who may be eligible for these tests, how to interpret results to avoid unnecessary intervention from over-detection, and the varying sensitivity levels of MCED tests across different cancers. Additionally, Tom shares insights into the Falcon trial – a major real-world study assessing a MCED test clinical performance and potential impact on early cancer detection and patient outcomes.

Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/

Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

In this special episode, Chadi gives up the microphone to guest host Kelly Ryerson, who takes over the show asking questions about Chadi's new book "The Cancer Journey."

What inspired the book writing? What methods are used? Who is the target audience? What did the author learn? And what did he aim to achieve?

Written for everyone who wants to learn more about cancer, this discussion highlights behind-the-scenes information on Chadi's latest achievement.

View more and order “The Cancer Journey.”

chadinabhan.com/the-cancer-journey/

Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/

Watch all Healthcare Unfiltered episodes on YouTube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA