Healthy Dialogue

A new trial assessed whether balloon angioplasty plus aggressive medical management was superior to aggressive medical management alone for patients with symptomatic intracranial atherosclerotic stenosis. Author Zhongrong Miao, MD, PhD, from Beijing Tiantan Hospital, discusses the BASIS randomized clinical trial with JAMA Deputy Editor Christopher C. Muth, MD. Related Content:

• Balloon Angioplasty vs Medical Management for Intracranial Artery Stenosis
• Is Balloon Angioplasty the Future for Intracranial Stenosis?

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The abating COVID-19 pandemic brings attention to rising mortality rates from non-COVID causes in the US, a trend that predates the COVID-19 pandemic. Viewpoint author Steven H. Woolf, MD, MPH, discusses this and more with JAMA Executive Editor Gregory Curfman, MD. Related Content:

• Increasing Mortality Rates in the US, but Not From COVID-19

Nonhormonal treatments for menopausal vasomotor symptoms may benefit symptomatic patients who cannot take or prefer to avoid systemic hormones. Author JoAnn V. Pinkerton, MD, MSCP, discusses the efficacy and safety of elinzanetant for the treatment of moderate to severe vasomotor symptoms associated with menopause with JAMA Deputy Editor Linda Brubaker, MD, MS. Related Content:

• Elinzanetant for the Treatment of Vasomotor Symptoms Associated With Menopause
• A New Era in Menopause Management?

To address the need to characterize long COVID in children and adolescents, the National Institutes of Health funded a pediatric program in the Researching COVID to Enhance Recovery (RECOVER) Initiative. Editorialist Suchitra Rao, MBBS, MSCS, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, discusses this and more with JAMA Senior Editor Tracy A. Lieu, MD, MPH. Related Content:

• Uncovering Long COVID in Children
• Characterizing Long COVID in Children and Adolescents

A new study looks at uterus transplant to determine if it is safe, feasible, and results in births of healthy infants. Editorialist Emily Jungheim, MD, MSCI, Northwestern University, discusses this innovative treatment with JAMA Deputy Editor Linda Brubaker, MD, MS. Related Content:

• Uterus Transplant—The Frontier of Innovative Fertility Treatment
• Uterus Transplant in Women With Absolute Uterine-Factor Infertility

Ten percent of US adolescents use e-cigarettes, and many want to quit. However, evidence on the effectiveness of vaping cessation interventions is lacking. Amanda L. Graham, PhD, of the Truth Initiative discusses with JAMA Senior Editor Tracy Lieu, MD, MPH, how a tailored, interactive text message intervention increased vaping cessation among adolescents recruited via social media channels. Related Content:

• A Vaping Cessation Text Message Program for Adolescent E-Cigarette Users
• Supporting Adolescents' Desire to Quit E-Cigarettes
• What Are E-Cigarettes?
• Variability in Constituents of E-Cigarette Products Containing Nicotine Analogues
• E-Cigarette Use in Adults
• Controversial FDA Decision Authorizes Menthol-Flavored E-Cigarettes Despite Risks to Youth
• Vaping in Youth
• E-Cigarette Use in Adolescents and Adults—A JAMA Collection

Gestational age estimation is foundational for obstetric care. In resource-limited settings, an integrated AI tool allows novice users to improve gestational age estimates. Author Jeffrey Stringer, MD, University of North Carolina, joins JAMA Deputy Editor Linda Brubaker, MD, MS, to discuss Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps. Related Content:

• Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps
• Enhancing Obstetric Ultrasonography With Artificial Intelligence in Resource-Limited Settings

Biomarkers for Alzheimer disease (AD) provide insight into disease processes and may aid clinical diagnosis for individuals with cognitive impairment. Author Stephen Salloway, MD, MS, of Brown University joins JAMA Deputy Editor Christopher Muth, MD, to discuss 2 articles and an accompanying editorial about blood biomarkers for AD and potential implications for clinical practice. Related Content:

• Are Blood Tests for Alzheimer Disease Ready for Prime Time?
• Blood Biomarkers to Detect Alzheimer Disease in Primary Care and Secondary Care
• Changes in Alzheimer Disease Blood Biomarkers and Associations With Incident All-Cause Dementia

Ulcerative colitis can significantly decrease quality of life. A third of patients have persistent symptoms with tumor necrosis factor inhibitors and nearly 1 in 5 patients will be hospitalized within 5 years of diagnosis. Author Gilaad G. Kaplan, MD, MPH, of the University of Calgary joins JAMA Associate Editor John M. Inadomi, MD, to discuss Risankizumab for Ulcerative Colitis. Related Content:

• Monoclonal Antibody Risankizumab for Ulcerative Colitis
• Risankizumab for Ulcerative Colitis

What are the ovarian cancer risks associated with endometriosis subtypes? Author Karen C. Schliep, PhD, MSPH, of the University of Utah joins JAMA Deputy Editor Linda Brubaker, MD, MS, to discuss Endometriosis Typology and Ovarian Cancer Risk. Related Content:

• Endometriosis Typology and Ovarian Cancer Risk
• New Insights in Endometriosis Subtypes and Ovarian Cancer Risk