Dr. Wali shares her “Grimm” audition story and then she and Sean talk about being a leader and being led. David Giuntoli explains the as yet unheard mystery of his hearing loss.

Sean and Dr. Wali talk about the pressures of aging. Max Greenfield is haunted by medical fears, and tells of spitting blood and dealing with grief and loss.

Spoiler alert: Sean is sensitive, now backed by science. Miranda Cosgrove is as confused as we are about the surprise puncture in her leg after ankle surgery.

Sean and Dr. Wali dive into sound baths and saddle up for equine assisted psychotherapy. Kevin Nealon goes deep about his recent prostate exam, his peripheral neuropathy, and A-Fib.

Priyanka explains PRP (platelet-rich plasma) to Sean so he can finally understand what his doctors injected into his knee. Jim Jefferies talks out of his ***hole about his hemorrhoids and diverticulitis and how his first kiss turned into Glandular Fever (mono).

Sean reveals the truth about his torn meniscus. Hint: He doesn’t have one. Chris Colfer “spits” out his parotitis story and why he feels no glee about his hip surgery.

Find out why Sean is wearing a foot boot and hear Dr. Wali explain the connection between a peanut allergy and a lung transplant. Dr. Sanjay Gupta talks about his double life in medicine and as a public figure. And don’t miss his story of performing emergency life saving brain surgery with a Black & Decker drill.

Sean celebrates Priyanka’s birthday and Priyanka shares her obsession with the Netflix show, “Glow Up: Britain’s Next Make-Up Star.” Joel McHale shares his journeys through dyslexia, memory loss, and his seven concussions.

Sean gives an ear infection update and Priyanka does a gut-check and learns she has H-pylori after a long bout of eczema. Cedric The Entertainer tells his hip replacement story and shares his passion for shedding light on diabetic nerve pain.

Sean’s affection for his dog gets him an ear infection and Priyanka prevents his panic over the arthritis in his foot. Anders Holm makes Sean squirm as he describes in detail his love for LASIK eye surgery and shares his experience inheriting Dupuytren's contracture.