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Episode 7! In this episode we discuss CAPECOD or  "Hydrocortisone in Severe Community-Acquired Pneumonia" by Dequin et al published NEJM 2023. No second article because this was an important trial which has a lot of messy history that we review, including the ESCAPe trial published last year, before we start our discussion.

We start with a listener question about 3SITES so if you want to skip ahead to the discussion on CAPECOD you can by skipping to the 8:45 time mark

CAPECOD: https://pubmed.ncbi.nlm.nih.gov/36942789/
ESCAPe: https://pubmed.ncbi.nlm.nih.gov/35723686/
CHEST Meta-analysis: https://pubmed.ncbi.nlm.nih.gov/36087797/
Individual Patient Meta-analysis: https://pubmed.ncbi.nlm.nih.gov/29020323/

If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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Episode 6! In this episode we discuss 1) "Treating Rhythmic and Periodic EEG Patterns in Comatose Survivors of Cardiac Arrest" by Ruijter et al published NEJM 2022 and 2) "Dexamethasone treatment for the acute respiratory distress synrome" by Villar et al published Lancet Respiratory Medicine 2020. 

This episode is a little bit longer than normal because we also extended our conversation of steroids in ARDS to the LaSRS (steroids in late ARDS) and Meduri 2007 methylprednisolone in early ARDS studies!

TELSTAR: https://pubmed.ncbi.nlm.nih.gov/35196426/
DEXA-ARDS: https://pubmed.ncbi.nlm.nih.gov/32043986/
Steroids in ARDS CHEST Point: https://pubmed.ncbi.nlm.nih.gov/33422200/
and Counterpoint: https://pubmed.ncbi.nlm.nih.gov/33422201/

If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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Episode 5! In this episode we again go to a new and old article 1) "Spontaneous-Breathing Trials with Pressure-Support Ventilation or a T-piece" by Thille et al published NEJM 2022 and 2) "Intravascular Complications of Central Venous Catheterization by Insertion Site" or "3SITES" by Parienti et al published NEJM 2015. 

SBT Strategies: https://pubmed.ncbi.nlm.nih.gov/36286317/
3SITES: https://pubmed.ncbi.nlm.nih.gov/26398070/

If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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EPISODE 4! In this episode we are SUPER excited to welcome friend of the podcast Whitney Gannon who is our local ECMO expert to talk about the inspiration for her research in ECMO (ECMO liberation and anticoagulation practices in ECMO) AND the INCEPTION trial, or the Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest paper publish in NEJM January 2023 by Suverein et al. This is a little bit of a long episode so some time marks to help you navigate if needed. 14:50 - talking about jargon we HATE. 18:35 - start of discussion of the trial. 35:58 - tangent on drone delivered AED

If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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BONUS Episode Time! Right after we started the podcast where one of the episodes was the TEAM trial for early mobilization, SCCM happened and there was yet another early mobilization trial. Since we just had an early mobility discussion we decided to drop our thoughts on this, how it relates to TEAM, and a related meta-analysis in bonus episode! Today we talk about 1) "Effect of early mobilisation on long-term cognitive impairment in critical illness in the USA: a randomized controlled trial" and 2) "The Effect of Mobilization at 6 Months after Critical Illness - Meta-Analysis"

If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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Episode 3! In this episode switch it up and review 2 NEW articles that published with SCCM 2023 1)"Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension" or CLOVERS by the PETAL Network published NEJM 2023 and 2) "Effect of Non-Invasive Ventilation After Extubation in Critically Ill Patients with Obesity in France" by De Jong et al published Lancet Respiratory medicine 2023. 

If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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Episode 2! In this episode we again go to a new and old article 1)"Early Active Mobilization during Mechanical Ventilation in the ICU" by the ANZICS group published NEJM 2022 and 2) "Albumin Replacement in Patients with Severe Sepsis or Septic Shock" by Caironi et al published NEJM 2014. 

If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

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Episode 1! In this episode we talk about what we're all about and dive right into our first two articles 1)"Defibrillation Strategies for Refractory Ventricular Fibrillation" by Cheskes et al published NEJM 2022 and 2) Comparison of Dopamine and Norepinephrine in the Treatment of Shock by De Backer et al published NEJM 2010. 

If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at [email protected] with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!