A meta-analysis of antidepressant doses and responses finds no evidence of improved outcomes with higher doses, just more side effects. However, this conclusion is based on fixed-dose comparison studies, which do not mirror the way we practice. Here we'll compare the lack of evidence for a dose-response relationship to your clinical practice.

Faculty:  Jim Phelps Hosts: Jessica Diaz, M.D.; Flavio Guzman, M.D.

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• Earn 0.5 CMEs: Quick Take Vol. 24
• In Search of a Dose-Response Relationship in SSRIs—A Systematic Review, Meta-Analysis, and Network Meta-Analysis