Inside Schizophrenia

Innovations in Schizophrenia Treatment


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Since the 1950s, the go-to treatment for schizophrenia has been oral antipsychotics. However, the landscape of schizophrenia treatment is changing and evolving, from advancements in antipsychotic long-acting injections to promising new treatments targeting muscarinic receptors to different types of neuromodulation stimuli of the brain, and even new theories connecting schizophrenia to other diseases like chronic traumatic encephalopathy (CTE).

Host Rachel Star Withers, a diagnosed schizophrenic, and co-host Gabe Howard explore the innovations in schizophrenia treatment in this episode of “Inside Schizophrenia.” Psychiatric Mental Health Nurse Practitioner Desiree Matthews, who is at the forefront of helping people with treatment-resistant depression and schizophrenia, joins as a guest to discuss some of the current and upcoming treatments.

To learn more -- or read the transcript -- please visit the official episode page.


Our guest, Desiree Matthews, PMHNP-BC, is a board certified psychiatric nurse practitioner with over a decade of experience in mental health treatment, providing top-tier care for those living with severe and persistent mental illness. Desiree is the founder and clinical director of Different Mental Health Program (MHP), which provides a virtual, personalized, and holistic approach to mental health care for patients in North Carolina. In addition to clinical practice, she serves as a member of the steering committee for US Psych Congress and has served faculty appointments with US Psych Congress, Psych Elevate, NP Institute, and with NEI. She is passionate about bringing practical future-focused healthcare education to healthcare providers to improve their patient outcomes.


Rachel Star Withers creates videos documenting her schizophrenia, ways to manage and let others like her know they are not alone and can still live an amazing life. She has written Lil Broken Star: Understanding Schizophrenia for Kids and a tool for schizophrenics, To See in the Dark: Hallucination and Delusion Journal. Fun Fact: She has wrestled alligators. To learn more about Rachel, please visit her website, RachelStarLive.com.


Our cohost, Gabe Howard, is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular book, "Mental Illness is an Asshole and other Observations," available from Amazon; signed copies are also available directly from the author.

Gabe makes his home in the suburbs of Columbus, Ohio. He lives with his supportive wife, Kendall, and a Miniature Schnauzer dog that he never wanted, but now can’t imagine life without. To learn more about Gabe, please visit his website, gabehoward.com.

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