In this episode of the JACC: Asia podcast, Editor-in-Chief Jian'an Wang provides a concise summary of the November 2024 issue, featuring five impactful studies on cardiovascular and metabolic health in Asian populations. Highlights include research on patient mismatch after aortic valve replacement, outcomes of mitral valve repair, and genetic links between lipid levels and type 2 diabetes risk, underscoring the importance of personalized healthcare approaches for Asian patients.