1) Pregnancy outcomes in aquaporin-4 positive neuromyelitis optica2) What's Trending: Safety and tolerability of resveratrol for Alzheimer disease3) Topic of the month: Endovascular Stroke Therapy This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Melanie Ward interviews Dr. Maria Isabel S. Leite about her paper on pregnancy outcomes in aquaporin-4 positive neuromyelitis optica. Dr. Ted Burns is interviewing Dr. R. Scott Turner for our “What's Trending” feature of the week about his paper on a randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease. In the next part of the podcast Dr. Prachi Mehndiratta interviews Dr. Pooja Khatri about the topic of broad overview of the new clinical trials in endovascular stroke therapy. DISCLOSURES: Dr. Leite serves as an editorial board member for Neuromuscular Disorders; has received travel grant and speaking honoraria from Biogen Idec and travel grant from Novartis; is supported by NHS National Specialized Commissioning Group for Neuromyelitis Optica, UK and by NIHR Oxford Biomedical Research Centre.Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with UCB, CSL Behring, Walgreens and Alexion Pharmaceuticals, Inc.Dr. Turner serves on the data safety and monitoring board for the National Institute on Aging; serves as an editorial board Member for Frontiers in Neuroscience and Neuropsychology and Cognition; receives research support from the National Institute on Aging.Dr. Khatri provided expert witnessing for stroke cases over last two years; receives research support from Penumbra, Inc, Genentech, Inc. and the NIH.