Today Razib talks to Jason Scharf, a biotech investor and podcaster. A native of San Diego, Scharf is an angel investor and startup advisor focused on the intersection of biology, technology, and business, particularly within TechBio and digital health. He has leadership experience in strategy and market intelligence at major companies like Illumina and Amgen. Scharf now targets investments in the bio-innovation tech stack and care delivery transformation. Additionally, as the host of the Austin Next podcast, he is an advocate for regional innovation ecosystems. Scharf promotes the growth of the Texas Triangle as a premier global hub for biotechnology and frontier tech.

Razib and Scharf discuss the growth and appeal of Austin, Texas, highlighting its booming tech scene and business environment. Scharf discusses why he moved from San Diego during the COVID-19 pandemic. They compare Austin's population growth to other major cities, noting Austin's rapid expansion from 400,000 in 1990 to over a million in 2020. They also talk about the impact of autonomous vehicles, the potential for high-speed rail, and the importance of infrastructure and talent in sustaining Austin's future growth. The conversation touches on the broader Texas Triangle and its economic significance to the American economy today and in the future. They highlight the libertarian and business-friendly environment in Texas, allowing for significant developments like Tesla's Gigafactory (the world's second-largest building), and the planned Terfab. Razib compares Austin and San Antonio, noting the former's rapid growth and the challenges it faces, such as infrastructure and housing. They also touch on the cultural and economic dynamics in Texas, emphasizing the importance of storytelling and narrative in shaping the state's future.