JHLT: The Podcast

JHLT: The Podcast kicks off 2022 with a look back at 2021! Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, joins the JHLT Digital Media Editors for a recap of the past year of The Journal of Heart and Lung Transplantation.

Studies include:

• Macdonald, et al, "The impact of frailty on mortality after heart transplantation," Feb 2021 JHLT
• Glinton, et al, "Bone marrow-derived AXL tyrosine kinase promotes mitogenic crosstalk and cardiac allograft vasculopathy," June 2021 JHLT
• Jang, et al, "Donor-derived cell-free DNA accurately detects acute rejection in lung transplant patients, a multicenter cohort study," Aug 2021 JHLT
• Scheuer, et al, "Heart transplantation following donation after circulatory death: Expanding the donor pool," Sep 2021 JHLT

Follow along at www.jhltonline.org/current, or, if you're an ISHLT member, log in at ishlt.org/journal-of-heart-lung-transplantation. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

It's time for the final episode of JHLT: The Podcast for 2021! Join Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors for two interviews with authors from the December issue of The Journal of Heart and Lung Transplantation. Both studies focus on protein biomarkers in thoracic transplantation.

First, the editors speak with Tereza Martinu, MD, MHS, Assistant Professor and Clinician at Toronto General Hospital. Dr. Martinu is the lead author on a paper entitled "Bronchoalveolar lavage cytokine-based risk stratification of minimal acute rejection in clinically stable lung transplant recipients." Beginning at 1:45, Erika Lease, MD, and David Schibilsky, MD, interview Dr. Martinu about the findings of the study and potential future application in clinical settings.

Starting at 13:35, Van-Khue Ton, MD, PhD, and Marty Tam, MD, are in conversation with Lauren Truby, MD, Cardiology Fellow at Duke University Medical Center, about her study from the December issue: "Proteomic profiling identifies CLEC4C expression as a novel biomarker of primary graft dysfunction after heart transplantation." Dr. Truby discusses her team's work on PGD, the expression of CLEC4C in transplant patients, and future potential work in the field.

Follow along in the December issue at www.jhltonline.org/current, or, if you're an ISHLT member, log in at ishlt.org/journal-of-heart-lung-transplantation. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

This episode of JHLT: The Podcast, but not the studies within, is sponsored by Paragonix.

JHLT: The Podcast is back with an all-pediatric episode for November! Join Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors for TWO interviews with authors from the November issue of The Journal of Heart and Lung Transplantation.

First, the editors speak with Dr. Richard Issitt, FCCP, from the perfusion department at Great Ormond Steret Hospital in London. Dr. Issitt is the lead author on a paper entitled "Intraoperative anti-A/B immunoadsorption is associated with significantly reduced blood product utilization with similar outcomes in pediatric ABO-incompatible heart transplantation." Beginning at 2:05, Erika Lease, MD, interviews Dr. Issitt about the goals and findings of the study, plus potential clinical criteria and future studies.

Starting at 15:30, Van-Khue Ton, MD, PhD, and Marty Tam, MD, are in conversation with Joseph Rossano, MD, MS, FAAP, FACC, head of the division of cardiology at the Children's Hospital of Philadelphia, about his group's study from the November issue: "The influence of mechanical Circulatory support on post-transplant outcomes in pediatric patients: A multicenter study from the International Society for Heart and Lung Transplantation (ISHLT) Registry." Dr. Rossano discusses the discontinuation of HVAD, linkage of ECMO to poor outcomes in pediatric patients, the safety of VAD implantation, and application in CHD patients.

Follow along in the November issue at www.jhltonline.org/current, or, if you're an ISHLT member, log in at ishlt.org/journal-of-heart-lung-transplantation. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

This episode of JHLT: The Podcast, but not the studies within, is sponsored by Paragonix.

It's October on JHLT: The Podcast! Join Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, for a discussion with the JHLT Digital Media Editors about two studies in the October issue of The Journal of Heart and Lung Transplantation.

First, the editors have the pleasure of interviewing Stephen Hoole, MA, BM, BCh, DM, FRCP, FESC, FACC, Consultant Interventional Cardiologist at Royal Papworth Hospital and Honorary Senior Visiting Fellow at the University of Cambridge. Dr. Hoole is a the senior author on a paper entitled "Serial right heart catheter assessment between balloon pulmonary angioplasty sessions identify procedural factors that influence response to treatment." Beginning at 1:34, Erika Lease, MD, and Marty Tam, MD, interview Dr. Hoole about the findings and applications of the paper and how it can benefit PH patients.

Starting at 13:00, Dr. Goldstein and David Schibilsky, MD, are in conversation about a second study from the October issue: "Reconditioning of circulatory death hearts by ex vivo machine perfusion with a novel HTK-N preservation solution," written by Saemann and colleagues in Heidelberg, Germany.

Follow along in the October issue at www.jhltonline.org/current, or, if you're an ISHLT member, log in at ishlt.org/journal-of-heart-lung-transplantation. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

This episode of JHLT: The Podcast, but not the studies within, is sponsored by Paragonix.

In the September 2021 episode of JHLT: The Podcast, Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, leads a discussion with the JHLT Digital Media Editors about two studies in the September issue of The Journal of Heart and Lung Transplantation.

Starting at 1:26, David Schibilsky, MD, Marty Tam, MD, and Van-Khue Ton, MD, PhD, discuss a paper from Benck and colleagues at Cedars-Sinai entitled "Recipient and surgical factors trigger severe primary graft dysfunction after heart transplant."

Starting at 12:27, Dr. Goldstein and Erika Lease, MD, discuss a study from Urso et al from Columbia University, called "Aspiration of conjugated bile acids predicts adverse lung transplant outcomes and correlates with airway lipid and cytokine dysregulation."

Follow along in the August issue at www.jhltonline.org/current, and learn more about the work of the ISHLT COVID-19 Task Force at ishlt.org/covid-19-information. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

This episode of JHLT: The Podcast, but not the studies within, is sponsored by Medtronic.

On this BONUS episode of JHLT: The Podcast, JHLT Editor-in-Chief Daniel R. Goldstein, MD, returns for an additional brief conversation with Saima Aslam, MD, MS, chair of the ISHLT COVID-19 Task Force. Dr. Aslam provides some key updates about vaccination for SARS-CoV-2 in organ transplant recipients, including updated efficacy information, recommendations about booster doses, and breakthrough infections.

Learn more about the work of the ISHLT COVID-19 Task Force, and get the latest publications and recommendations documents, at ishlt.org/covid-19-information. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

Welcome to the August 2021 episode of JHLT: The Podcast. In this special episode, Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, and the JHLT Digital Media Editors, interview ISHLT COVID-19 Task Force Chair Saima Aslam, MD, MS, about the latest, critical information on SARS-CoV-2 vaccinations in immunosuppressed thoracic organ transplant recipients.

The August issue of JHLT contains two key studies exploring COVID-19 vaccinations—one from Peled et al examining the safety and efficacy of the BNT162b2 mRNA vaccine in heart transplant recipients, and another from Havlin et al exploring lung transplantation.

In addition to summarizing and exploring these two papers, Dr. Aslam and the editors discuss additional topics related to COVID-19 vaccination, such as the difference in immune response between natural infection and vaccine, whether antibody testing is useful, and vaccine efficacy.

Follow along in the August issue at www.jhltonline.org/current, and learn more about the work of the ISHLT COVID-19 Task Force at ishlt.org/covid-19-information. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

This episode of JHLT: The Podcast—but not the studies within—is sponsored by CareDx.

Welcome to the July 2021 episode of JHLT: The Podcast! Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, leads a discussion with the JHLT Digital Media Editors about two studies in the July issue of The Journal of Heart and Lung Transplantation.

Starting at 1:45, Dr. Goldstein and Erika Lease, MD, discuss a paper from Sage, et al, at the University of Toronto, Canada, titled "Prediction of donor related lung injury in clinical lung transplantation using a validated ex vivo lung perfusion inflammation score."

Starting at 10:45, Van-Khue Ton, MD, PhD, and Marty Tam, MD, discuss a study from Rafei and colleagues from Minnesota and Houston, USA, called "Association between digoxin use and gastrointestinal bleeding in contemporary continuous flow left ventricular assist device support."

Follow along in the July issue at www.jhltonline.org/current. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

This episode of JHLT: The Podcast, but not the studies within, is sponsored by Paragonix.

The June episode of JHLT: The Podcast is now live, and features a first for the podcast—an interview with a JHLT author! In this episode, host Daniel R. Goldstein, MD, Editor-in-Chief of the Journal of Heart and Lung Transplantation, conducts an interview of Kiran Khush, MD, MAS, member of the ISHLT Board of Directors and Professor of Medicine and Director of Heart Transplant Research at Stanford University.

In the episode, Dr. Khush is interviewed by JHLT Digital Media Editors Erika Lease, MD, David Schibilsky, MD, and Van-Khue Ton, MD, PhD, on her state of the art review, entitled "Clinical utility of donor-derived cell-free DNA testing in cardiac transplantation," which appears in the June issue of JHLT.

During the discussion, Dr. Khush answers key questions about donor derived cell-free DNA and helps "de-mystify" the importance of this assay to listeners. This is a fascinating discussion with practical clinical applications that you won't want to miss.

Follow along in the June issue at www.jhltonline.org/current. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.com.

This episode of JHLT: The Podcast, but not the studies within, is sponsored by Medtronic.

JHLT: The Podcast is back with round table talks for the May 2021 issue of the Journal of Heart Transplantation. Daniel R. Goldstein, MD, Editor-in-Chief of JHLT, leads a discussion with the JHLT Digital Media Editors.

Starting at 1:36, Van-Khue Ton, MD, PhD, and Martin Tam, MD, discuss an paper from Dr. Englung and colleagues in Oslo, Norway, titled "Intravenous iron supplement for iron deficiency in cardiac transplant recipients (IronIC): A randomized clinical trial."

Starting at 9:04, Erika Lease, MD, and David Schibilsky, MD, discuss a study from Fessler et al in Paris, France, called "Operating room extubation: A predictive factor for 1-year survival after double-lung transplantation."

Follow along in the May issue at www.jhltonline.org/current. Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.com.

This episode of JHLT: The Podcast, but not the studies within, is sponsored by Paragonix.