Show Notes

In this special live episode from the 2025 North American Congress of Clinical Toxicology (NACCT), Ryan takes you inside the poster hall to hear directly from the researchers themselves. Covering 11 abstracts that span high-stakes management decisions, surprising case reports, and challenges to toxicology dogma, this year’s highlights feature everything from amlodipine overdoses to naturopathic misadventures, metformin-associated blindness, and more.

If you couldn’t make it to NACCT or just want to catch up on some of the most impactful new research in our field, this episode will give you a front-row seat. Check below for links to the published abstracts, the full list of studies discussed, and timestamps for where you can hear each one.

Link to published abstract manuscript

Preamble with Dr. Jon Cole

09:20 - Abstract #7. Is beta blocker toxicity associated with hypoglycemia?

• First author: Dr. Megan Audette

17:00 - Abstract #237. V-A ECMO as a treatment for vasoplegic shock in amlodipine poisoning: a comparison

• First author:Dr. Daniel Tirado

26:50 - Abstract #247. Blocked but not beaten: ECMO’s role in severe amlodipine toxicity – a poison center case series?

• First author: Dr. Carlos Saldarriaga

28:15 Abstract #27. Amlodipine double-dose therapeutic errors reported to Poison Centers

• First author: Carlos Saldarriaga

29:00 Abstract #27. Dosing on the edge: unpacking inadvertent amlodipine ingestions reported to a single poison center

• First author: Dr. Tiana Patriarca

32:38 - 292. Intravenous administration of sodium zirconium cyclosilicate resulting in death

• First author: Dr. Stephen Thornton

Abstracts & Guests

40:06 – Abstract #21. Quantitative analysis of amlodipine removal by plasmapheresis

• Guest: Dr. Keahi Horowitz, MD – Acute and Intensive Care Research Award winner

44:00 – Abstract #23. Relationship between reported ingestion dose and outcome in amlodipine poisoning

• Guest: Dr. Colleen Cowdery, MD

47:30 – Abstract #24. Management of severe amlodipine toxicity with high-dose calcium alone

• Guest: Dr. Vincent Ma, MD

53:00 – Abstract #70. Iatrogenic exposure to long-acting buprenorphine injectable in an opioid-naïve patient

• Guest: Dr. Connor Young, MD

55:51 – Abstract #182. Left in the dark: a case of blindness in the setting of metformin toxicity

• Guest: Madison Bompard, MD

57:56 – Abstract #169. Just because it’s natural doesn’t mean it’s safe: a case of pediatric toxicity from topical and herbal remedies

• Guest: Dr. Aria Darling, MD

59:57 – Abstract #203. Serotonin syndrome after vaping "Moocah"

• Guest: Dr. Connor Murphy, DO

1:03:00 – Abstract #307. Intravenous ozone autohemotherapy: a retrospective observational case series

• Guest: Nicole McLarty

1:05:59 – Abstract #134. Do they really need n-acetylcysteine? Exploratory analysis of outcomes in patients with elevated liver function tests but no detectable acetaminophen

• Guest: Dr. Seth Carroll PharmD

1:09:30 – Abstract #130. Outcomes of acute acetaminophen-poisoned patients treated with and without fomepizole: a Toxic registry study

• Guest: Dr. Jordan Woollum, PharmD

1:15:30 – Abstract #295. Evaluation of onset and resolution of complications after chronic methotrexate poisoning

• Guest: Dr. Van Quach, PharmD

1:19:13 – Abstract #325. Implications of potassium in salicylate toxicity treated with urinary alkalinization

• Guest: Dr. Andrew Yetka, PharmD

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