Join us for an in-depth discussion on Acute-on-Chronic Liver Failure (ACLF) with Dr. Christina Lindenmeyer, board-certified transplant hepatologist at the Cleveland Clinic and founder of their groundbreaking Medical Intensive Liver Unit (MILU).

Dr. Lindenmeyer, who serves as Vice Chair of the AASLD ACLF Special Interest Group, breaks down the essential definitions and diagnostic criteria of ACLF, explores evidence-based management strategies, and shares insights from her extensive research in liver failure and transplantation.

We are excited to announce we have two new fellow hosts, Vlad Fomin and Dilara Hatipoglu! They are so excited to spend the year with you all learning about the liver. Listen to the end as we debut a brand new lightning round!

In Liver we trust.

On this episode of Liver Talks, Gideon Hirschfield, the Lily and Terry Horner Chair in Autoimmune Liver Disease Research and Professor at the University of Toronto, comes on to talk about the latest advances in primary biliary cholangitis.

Also, we bid Patrick Lee adieu and set the stage for new fellow leads!

Hosts:
Patrick Lee
Adam Winters
Alex Vogel

Guests:
Gideon Hirschfield

Edited by:
Taylor Gouterman

Enjoy a fantastic talk with the master of portal hypertension, Guadalupe Garcia-Tsao. Perfect for listening whilst in transit to or from San Diego for AASLD!

We are looking for interested trainees to take the reins of fellow lead for Liver Talks next academic year (2025-2026). Feel free to e-mail [email protected] if you are interested in learning more.

Hosts:

Patrick Lee

Adam Winters

Alex Vogel @AlexSVogel

Guests: Guadalupe Garcia-Tsao  @ggarciatsao

Music Credits:

All music furnished by ⁠https://freemusicarchive.org/⁠ under Creative Commons licensing.⁠http://brokeforfree.com/⁠⁠https://jahzzar.bandcamp.com/⁠⁠https://blankkytt.bandcamp.com⁠

Big time guest alert!

Dr. Michael Lucey joins us to talk about all things ALD - including early LT and whether or not he uses steroids or steroids + NAC for severe AH. Which is it? You'll have to listen!

Hosts:
Patrick Lee
Adam Winters @adam_c_winters
Alex Vogel @AlexSVogel

Guests:
Michael Lucey
Robert Wilechansky @WilechanskyMD

Edited by:
Taylor Gouterman

Music Credits:

All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.
http://brokeforfree.com/
https://jahzzar.bandcamp.com/
https://blankkytt.bandcamp.com

After a respite, Liver Talks is back with a very special guest. We talk to Norah Terrault, Chief of Gastroenterology and Hepatology at Keck Medical Center of USC, about her career, the MASLD nomenclature change, and her work with AASLD. Then, Rob Wilechansky is back to walk us through the latest and greatest published in Hepatology.

Hosts:

Patrick Lee

Adam Winters @adam_c_winters

Alex Vogel @AlexSVogel

Guests:

Norah Terrault @norahterrault

Robert Wilechansky @WilechanskyMD

Edited by:

Taylor Gouterman

Music Credits:

“Tropkicks”, Broke for Free

“Something Elated”, Broke for Free

“Take Me Higher”, Jahzzar

“RSPN,” Blank & Kytt

All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.

http://brokeforfree.com/

https://jahzzar.bandcamp.com/

https://blankkytt.bandcamp.com/

Adam and Alex start by introducing the new fellow lead for Liver Talks, Patrick Lee - a GI fellow at USC. The bulk of the episode is spent discussing a recent paper Adam published about finding your first hepatology job after fellowship. They discuss when and how to apply, what to prioritize, and negotiation tactics. Finally, Rob Wilechansky drops by to discuss a PBC clinical trial recently published in Hepatology.

Jobs Paper: https://pubmed.ncbi.nlm.nih.gov/37309214/

PBC Trial: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344437/

Hosts:

Patrick Lee

Adam Winters @adam_c_winters

Alex Vogel @AlexSVogel

Guests:

Robert Wilechansky @WilechanskyMD

Edited by:

Taylor Gouterman

Music Credits:

“Tropkicks”, Broke for Free

“Something Elated”, Broke for Free

“Take Me Higher”, Jahzzar

“RSPN,” Blank & Kytt

All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.

http://brokeforfree.com/

https://jahzzar.bandcamp.com/

https://blankkytt.bandcamp.com/

On this episode of Liver Talks, Alex and Adam are joined by Amit Singal, HCC expert and Chief of Hepatology at UT Southwestern, for a fascinating conversation about the latest and greatest in HCC.

Then, a new segment is born featuring Rob Wilechansky, a transplant hepatology fellow at MGH and Hepatology's editorial fellow, in which they discuss an exciting new article from a recent issue of the journal.

AASLD HCC Guideline: https://journals.lww.com/hep/fulltext/9900/aasld_practice_guidance_on_prevention,_diagnosis,.441.aspx

Tropifexor plus cenicriviroc combination versus monotherapy in non-alcoholic steatohepatitis: Results from the Phase 2b TANDEM study:

https://pubmed.ncbi.nlm.nih.gov/37162151/

Hosts

Adam Winters @adam_c_winters

Alex Vogel @AlexSVogel

Guests:

Amit Singal @docamitgs

Robert Wilechansky @WilechanskyMD

Edited by:

Taylor Gouterman

Music Credits:

“Tropkicks”, Broke for Free

“Something Elated”, Broke for Free

“Take Me Higher”, Jahzzar

“RSPN,” Blank & Kytt

All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.

http://brokeforfree.com/

https://jahzzar.bandcamp.com/

https://blankkytt.bandcamp.com/

Alex and Adam are thrilled to host Liver Talks' first time return guest, Dr. Patty Pringle Bloom from the University of Michigan, to talk all about the microbiome and its relationship to liver disease, the International Society for Hepatic Encephalopathy and Nitrogen Metabolism, "lunatic asylums" in Germany and much more!

ISHEN: https://www.ishen.org/

Dr. Bloom's work (a curated selection):

FMT in HE: https://pubmed.ncbi.nlm.nih.gov/35384391/

Post-transplant ascites: https://pubmed.ncbi.nlm.nih.gov/37219847/

Hosts

Adam Winters @adam_c_winters

Alex Vogel @AlexSVogel

Guest:

Patty Pringle Bloom @BloomPringle

Edited by:

Taylor Gouterman

Music Credits:

“Tropkicks”, Broke for Free

“Something Elated”, Broke for Free

“Take Me Higher”, Jahzzar

“RSPN,” Blank & Kytt

All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.

http://brokeforfree.com/

https://jahzzar.bandcamp.com/

https://blankkytt.bandcamp.com/

There are new NASH Guidelines and we're gonna talk about them. Who better to chat with than lead author Dr. Mary Rinella? Probably nobody! But first, the precarities of being an NY Jets fan (sorry) and a heads up about the Liver Meeting abstract deadline.

AASLD NASH Guidelines:

https://journals.lww.com/hep/Fulltext/2023/05000/AASLD_Practice_Guidance_on_the_clinical_assessment.31.aspx

Hosts

Adam Winters @adam_c_winters

Alex Vogel @AlexSVogel

Guests:

Mary Rinella @marurinella

Edited by:

Taylor Gouterman

Music Credits:

“Tropkicks”, Broke for Free

“Something Elated”, Broke for Free

“Take Me Higher”, Jahzzar

“RSPN,” Blank & Kytt

All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.

http://brokeforfree.com/

https://jahzzar.bandcamp.com/

https://blankkytt.bandcamp.com/

On this episode of Liver Talks, Adam and Alex welcome their very good friend Dr. Ani Kardashian from the Keck School of Medicine at USC's Division of Gastroenterology and Liver Disease (3:40). She discusses her work focusing on the effect of food insecurity in patients with chronic liver disease, as well as her interest in disparities research.  It's a fascinating conversation that has profound implications on clinical practice. 

The episode ends with a review of some simple screening tools to help identify patients at risk of food insecurity (41:24)

Work Referenced in the Episode

Dr. Kardashian's work on food insecurity

https://pubmed.ncbi.nlm.nih.gov/36173037/

https://pubmed.ncbi.nlm.nih.gov/34958747/

Dr. Kardashian's encompassing review on disparities in liver disease

https://pubmed.ncbi.nlm.nih.gov/35993341/

Hosts

Adam Winters @adam_c_winters

Alex Vogel @AlexSVogel

Guests:

Ani Kardashian @AniKardashianMD

Music Credits:

“Tropkicks”, Broke for Free

“Something Elated”, Broke for Free

“Take Me Higher”, Jahzzar

“RSPN,” Blank & Kytt

All music furnished by https://freemusicarchive.org/ under Creative Commons licensing.

http://brokeforfree.com/

https://jahzzar.bandcamp.com/

https://blankkytt.bandcamp.com/