When Carol Offen’s son needed a kidney, she did not hesitate to offer her own, but she still had a lot of questions. In the United States, nearly 100,000 people are waiting for a kidney transplant with waitlists as long as five years or more, and every day 12 people die of kidney disease. As a result, living kidney donations have become increasingly popular. We talk to Offen, co-author of the book “The Insider’s Guide to Living Kidney Donation,” and Dr. Nancy Ascher, an organ transplant expert who is also a kidney donor, about organ transplants and what it takes to make what organ recipients call, “the greatest gift.”

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