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Dr Khan interviews Dr. Julia Moore-Vogel, Scripps Researcher and lead scientist of the new study using tirzepatide to treat Long COVID. The study is called LoCITT-T, and it is actively enrolling participants. They discuss the study's design, eligibility criteria, and the potential benefits of the drug. Julia shares her personal experience with long COVID and how it has influenced her work. The conversation also covers the importance of making clinical trials accessible to those with disabilities and the innovative use of wearable technology in the study.

Keywords

Long COVID, tirzepatide, clinical trial, disability, wearable technology

Resources:

Long COVID Treatment Trial-Tirzepatide (LoCITT-T): https://www.longcovid.scripps.edu

Fatigue Severity Scale: https://www.med.upenn.edu/cbti/assets/user-content/documents/Fatigue%20Severity%20Scale%20(FSS).pdf

FUN-CAP 27: https://batemanhornecenter.org/wp-content/uploads/2023/12/FUNCAP27-questionnaire.pdf

DSQ-COVID: https://www.researchgate.net/publication/360476212_DePaul_Symptom_Questionnaire-COVID

Eric Topol, MD Ground Truths: https://erictopol.substack.com/

All of Us Research Hub: https://www.researchallofus.org/ 

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In this episode of Long COVID MD, Dr. Zeest Khan is joined by Katherine Marie, an nurse practitioner, long COVID patient, and podcast host. They discuss ways to navigate the holiday season while managing long COVID. They share personal experiences and strategies for maintaining health and energy, such as planning energy like a budget, setting boundaries, and building recovery time into schedules. The conversation highlights the importance of self-compassion and adapting traditions to fit current capabilities.

Hear more from Katherine Marie: https://longcovidrealtalk.com/

Keywords

Long COVID, holiday season, energy management, self-compassion, setting boundaries

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Read the Newsletter: https://longcovidmd.substack.com/p/nasal-sprays-a-sure-fire-way-to-reduce?r=478j9x

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In this episode, Dr. Zeest Khan discusses the importance of nasal hygiene in reducing inflammation and preventing infections. She shares practical tips and techniques, including the use of saline and oxymetazoline, to open congested nasal passages. Dr. Khan also highlights the role of nasal steroids and antihistamines in managing symptoms, especially for those with long COVID and allergies.

Keywords

nasal hygiene, inflammation, saline, oxymetazoline, nasal steroids, antihistamines, long COVID, allergies, nasal passages, health tips

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In this conversation, Dr. Zeest Khan discusses how she manages acute infections while dealing with the ongoing effects of long COVID. To recover quickly and reduce side effects of medications, she teaches you to personalize your treatment. In this episode you'll learn the 4 categories of cold medicines, common side effects, and how to read a medication label effectively. Take exactly what you need, and ONLY what you need to recover from an upper respirator infection FAST.

Links:

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Newsletter for this Episode available November 4, 2025. Sign up so you don't miss it!
Hydration the Right Way

Chapters
00:00 Personalized Cold Care Matters
01:11 My Story
02:08 Medical Disclaimer
02:36 Understanding OTC Cold Meds
03:03 Decongestants and Their Effectiveness
03:48 Four Categories of Cold Meds
04:08 Pain/Fever
04:21 Pick the Right Decongestant
04:58 Antihistamines Explained
07:09 Side Effects of Decongestants
07:57 Antihistamines
09:01 Join the Community!
09:19 Tailoring Treatment to Individual Needs
09:52 Cough Meds
11:05 Practical Application of Cold Care
12:07 The Importance of Pain Management
13:31 Personal Experience with Cold Treatment
15:00 Why You Need Personalized Treatment
15:36 Rest, Hydrate, & Stay Positive

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Is scientific research vulnerable to political instability? Dr. Zeest Khan explains how the current US government shutdown could disrupt the billion-dollar NIH RECOVER project, delay clinical trials, and jeopardize the chances of discovering effective treatment. Guests Michael Sieverts and Ezra Spier share insider perspectives on why transparency, stable funding, and patient collaboration are essential to saving Long COVID research and restoring trust in science.

Read more on this topic at Substack

Referenced Episodes:

Tylenol-COVID Connection

Takeaways from RECOVER-TLC 2025

Episode 18: Long COVID Advocacy

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I’m pleased to share this recording of my conversation with Dr Alyssa Burgart, a pediatric anesthesiologist and medical bioethicist who writes Poppies & Propofol. We discussed our concerns about the US Health Department’s new —and puzzling — claims that acetaminophen, the active ingredient in Tylenol, causes autism. 

We covered the importance of drug safety, the impact of misogyny in medical care, and the link to long COVID.

If you missed my last post on the topic, read the full story here:

If You Care About COVID, You Should Care About Tylenol

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Episode 47: Is Health a Moral Obligation? https://www.buzzsprout.com/2253656/episodes/17011381

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The NIH’s RECOVER initiative just held its 2nd annual workshop-- Pathways to Treatment — and here’s what you need to know. In this episode, Dr Khan shares key updates on Long COVID research from RECOVER 2025, including patient voices, new treatments under study, and where the research is headed next.

Listen to Episode 19: Low Dose Naltrexone

We’ll cover:
 ✔️ The role of patient advocates in shaping research
 ✔️ Interventions under study: low-dose naltrexone, baricitinib, GLP-1 receptor agonists, and stellate ganglion blocks
 ✔️ Challenges with access and equity in treatment
 ✔️ What’s next for clinical trials in Long COVID

As both a physician and a patient with Long COVID, Dr Khan brings you a unique perspective on what this research means for patients, clinicians, and the future of care.

🔔 Subscribe for more updates on Long COVID research, treatments, and patient perspectives.
👍 Like this episode if you find it helpful, and share it with others navigating Long COVID.

More resources:
👉 Learn more about RECOVER: https://recovercovid.org

👉 Follow my work on Long Covid, MD: longcovidmd.substack.com

Keywords: Long COVID research update, RECOVER 2025, NIH RECOVER TLC workshop, Long COVID new treatments, low dose naltrexone Long COVID, GLP-1 Long COVID, baricitinib Long COVID, stellate ganglion block Long COVID, Long COVID patient advocacy, Long Covid MD

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🔔 Subscribe for more science-backed insights
📖 Read the full newsletter + reference sheet
💬 Share your experience with hydration strategies in the comments—I’d love to hear from you!

Living with Long COVID or POTS often means battling dizziness, fatigue, and brain fog caused by low blood volume. In this episode, Dr Khan breaks down the science of hydration and explain how different fluids—plain water, salt water, and oral rehydration solutions (ORS)—actually work in your body.

You’ll learn:
 ✅ Why plain water gives a quick but short-lived boost
 ✅ How salt water helps your body hold onto fluid
 ✅ Why oral rehydration solutions like WHO ORS and St. Mark’s formula can act almost like IV saline
 ✅ The difference between medical ORS and common sports drinks like Gatorade, Pedialyte, and Liquid IV
 ✅ How the sodium-glucose transporter (SGLT1) “supercharges” absorption

Hydration is more than just drinking water—it’s about strategic plasma expansion to keep blood flowing to your brain and reduce symptoms of dysautonomia.

⚠️ Safety note: Salt loading isn’t for everyone. Check with your doctor if you have kidney disease, heart failure, uncontrolled hypertension, or a tendency to swelling.

👩‍⚕️ I’m Dr. Zeest Khan, a physician and patient with Long COVID. On Long Covid, MD, I simplify medical science to help you make better decisions about your care and recovery.

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Watch the video on YouTube

Can IV fluids really help with Long COVID symptoms like fatigue, dizziness, and brain fog? In this episode, Dr Khan reviews the scientific evidence on IV hydration versus oral rehydration solutions (ORS) in children, athletes, and patients with POTS (postural orthostatic tachycardia syndrome)—and shares her personal experience as both a doctor and a patient living with Long COVID.

You’ll learn:
✔️ How IV fluids expand blood volume and why that matters in Long COVID
✔️ The risks and complications of IV therapy (including when NOT to use it)
✔️ What the research says about ORS vs. IV hydration in different groups
✔️ Why IV fluids may serve as a temporary rescue therapy for some people with POTS or Long COVID
✔️ Practical tips for safe IV use 

💡 Whether you’re exploring treatment options or just curious about the science, this episode breaks down what we know—and what we don’t—about IV hydration in Long COVID.

For links to studies and a printable summary of today's episode, subscribe to the newsletter.

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LCMD will be away for the summer. Will Dr Khan post anything in the meantime?? Find out by following her: 

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In this episode of Long COVID MD, Dr. Zeest Khan highlights a healthcare system that effectively mitigated the pandemic and maintained community trust, while facing numerous structural obstacles. Should we follow this model of medicine more broadly? She interviews Dr. Noha Aboelata, Family Medicine physician and CEO of Roots Community Health, who shares insights on Root's holistic approach to healthcare, the importance of community trust, and the need for accessible and equitable health services. Roots played a tremendous role in the beginning of the COVID-19 pandemic. The organization offered testing, recognized patterns of viral spread, and shared critical information with the public before, and sometimes in place of, government agencies. Roots' model of rebuilding community trust allowed them to respond quickly and effectively against the COVID-19 pandemic, and continues to serve the community well. The conversation highlights the role of community health in addressing systemic inequities and the significance of empowering patients to advocate for their own health.

People's Health Briefing

How Roots Pushed Medtronic to Improve Pulse Oximetry

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