1) Lower stroke risk with lower blood pressure in hemodynamic cerebral ischemia and 2) Topic of the month: Mitochondrial disorders. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Andy Southerland interviews Dr. William Powers about his paper on lower stroke risk with lower blood pressure in hemodynamic cerebral ischemia. Dr. Roy Strowd is reading our e-Pearl of the week about Déjà vu. In the next part of the podcast Dr. Maria Farrugia interviews Dr. Doug Turnbull about the management of mitochondrial disorders. The participants had nothing to disclose except Drs. Southerland, Powers and Strowd.Dr. Southerland serves as Podcast Deputy Editor for Neurology®; serves as Clinical Research Advisor for Totier Technologies, Inc.Dr. Powers serves as an editorial board member of Stroke and Journal of Cerebral Blood Flow and Metabolism; serves on the scientific advisory board for Ontario Brain Institute Morehouse School of Medicine; receives research support from the NIH and UNC.Dr. Strowd serves on the editorial team for the Neurology® Resident and Fellow Section.