Today, Dr. Mark Mandel, Professor of Medical Microbiology & Immunology at University of Wisconsin-Madison, joins the #QualityQuorum to discuss the research his laboratory group does exploring how the luminous bacterium Vibrio fischeri finds its way into its symbiotic partner, the Hawai’ian Bobtail squid Euprymna scolopes.  It will be an enlightening podcast!

Host: Mark O. Martin

Guest: Mark Mandel

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Links for this episode

•  A video for introductory #Micronauts about the squid-Vibrio symbiosis featuring science journalist Ed Yong and two founders of the field, Dr. Ned Ruby and Dr. Margaret McFall-Ngai.
• An engaging video about Euprymna scolopes, the larger partner in this symbiosis, described by Dr. McFall-Ngai.
• A more advanced overview to this field, authored by Dr. Ned Ruby, Dr. Eric Stabb, and Dr. Karen Visick.
• A very complete recent review of the field from Dr. Visick’s lab.  
• A video presentation by Dr. Mandel about this symbiosis.
• The first paper discussed by Dr. Mandel:  “Hybrid Histidine Kinase BinK Represses Vibrio fischeri Biofilm Signaling at Multiple Developmental Stages.”
• The second paper discussed by Dr. Mandel:  “High Levels of Cyclic Diguanylate Interfere with Beneficial Bacterial Colonization.”
• The third paper discussed by Dr. Mandel:  “Mobile-CRISPRi as a powerful tool for modulating Vibrio gene expression.”
• Dr. Mandel’s faculty website.
• Dr. Mandel’s laboratory website

Intro music is by Reber Clark

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