To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline

Guest: Atta Behfar, M.D., Ph.D. (@AttaBehfar)

Host: Darryl S. Chutka, M.D. (@ChutkaMD)

Traditional treatment of cardiac disease, especially advanced congestive heart failure has been limited. Transplantation has potential for benefit; however, organ shortage remains a barrier. It’s anticipated that regenerative medicine will help solve this unmet need with new treatment options to repair damaged heart tissue. This podcast will discuss regenerative medicine for cardiovascular disease with Dr. Atta Behfar, a Mayo Clinic cardiologist with expertise in advanced heart failure and transplantation. We’ll review the progress made in regenerative medicine in management of cardiovascular disease, what treatment options are currently available and the potential treatment options which will become available in the future.

Specific topics discussed:

• Regenerative potential of the cardiovascular system

 Additional resources:

• Clinical Trials available at Mayo Clinic through the Center for Regenerative Medicine: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/clinical-trials

 Additional educational opportunities from Mayo Clinic:

• https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

This episode is shared from Mayo Clinic Q&A and was recorded June 14, 2021

Guest:  Gregory A. Poland, M.D. (@drgregpoland) 

Host: Halena M. Gazelka, M.D. (@hmgazelkamd)   

The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices is holding an emergency COVID-19 meeting this week to discuss COVID-19 vaccine safety as it relates to news that young people may develop myocarditis after receiving a second dose of a messenger RNA COVID-19 vaccine.

Myocarditis, which is an inflammation of the heart muscle, is usually caused by a viral infection. But it can result from a reaction to a drug or be part of a more general inflammatory condition. Signs and symptoms include chest pain, fatigue, shortness of breath and arrhythmias.

"There have been about 789 cases reported," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "And that can happen for a whole variety of reasons." 

In this Mayo Clinic Q&A podcast, Dr. Poland details the concerns about the myocarditis reports. He also discusses the latest news on the COVID-19 delta variant, and he explains what scientists are calling the "two-track pandemic."

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Terry D. Schneekloth, M.D.

Host: Darryl S. Chutka, M.D. (@ChutkaMD)

According to the 2019 National Survey on Drug Use and Health, nearly 26% of individuals 18 and older reported that they engaged in binge drinking and slightly over 6% engaged in heavy alcohol use within the past month. Binge drinkers were 70 to 90 times more likely to have an alcohol-related emergency department visit. Based on their data from this study, they estimated that nearly 15 million people ages 12 and older had alcohol use disorder. It’s also known that those with alcohol use disorder commonly seek care from primary care providers for alcohol-related medical problems. Our guest for this podcast is Terry Schneekloth, M.D., a psychiatrist and addiction specialist at Mayo Clinic.

Specific topics discussed:

• Definition of alcohol use disorder

Additional Resources:

• World Health Organization (WHO). Alcohol Use Disorders Identification Test (AUDIT). 2001 November 18; https://www.who.int/publications/i/item/audit-the-alcohol-use-disorders-identification-test-guidelines-for-use-in-primary-health-care

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline

Guest: Nathan Staff, M.D. (@NathanStaffMD)

Host: Darryl S. Chutka, M.D. (@ChutkaMD)

The cells in our nervous system are extremely specialized, especially those in the brain. Unfortunately, nervous tissue does not have a great potential to regain function once it is lost. Exciting research is being done in the field of neuro-regenerative medicine which will give hope for improvement to those with chronic neurodegenerative disease or nerve damage from injury. Dr. Nathan Staff, a Mayo Clinic neurologist, joins us regarding the challenges with the current management of chronic neurodegenerative diseases and the future potential for treating such conditions as Parkinson’s Disease, Alzheimer’s Disease, ALS and other neurodegenerative disease with regenerative medicine therapies.

Specific topics discussed:

• Current research in regenerative medicine treatment for chronic neurodegenerative disease

 Additional educational opportunities from Mayo Clinic:

• https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Daniel B. Ryssman, M.D.

Host: Darryl S. Chutka, M.D. (@ChutkaMD)

Generally, we take our feet for granted. It’s not unusual for a person to take 8- to 10-thousand steps per day. That translates to over 115,000 miles in a lifetime. By the time we reach 70 years old, the average person will have walked the equivalent of 4 times around the globe. Yet, we stop taking our feet for granted when they hurt, and it’s estimated that 75% of Americans will experience foot problems of varying degrees of severity during their lifetime. In this podcast, we’ll discuss foot and ankle pain with Daniel Ryssman, M.D., an orthopedist and sports medicine physician from Mayo Clinic. We’ll review some of the common injuries to the ankle such as sprains and fractures as well as common chronic conditions of the foot such as plantar fasciitis and bunions. Dr. Ryssman delves into the best ways to prevent, diagnose, and treat these conditions as well as what, if any, imaging to order.

Specific topics discussed:

• Ankle sprains

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

This episode is shared from Mayo Clinic Q&A and was recorded June, 2021

To claim credit visit: https://ce.mayo.edu/covid19podcast 

Guest:  Gregory A. Poland, M.D. (@drgregpoland) 

Host: Halena M. Gazelka, M.D. (@hmgazelkamd)   

If you've been vaccinated for COVID-19, you're able to go shopping, eat in restaurants and travel on airplanes without the same worry of becoming infected with COVID-19 that existed just months ago. But for those who are unvaccinated, getting infected with COVID-19 — even with just minor symptoms — should be a concern, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group.

"For those who have been vaccinated, life is resuming back to a sense of normalcy," says Dr. Poland. "But for the unvaccinated, they now live in a dangerous phase of the pandemic, where we're seeing circulating variants that are much more transmissible and may cause worse cases of the disease than what happened last year at this time. I think the people who are unvaccinated may not realize that."

In this Mayo Clinic Q&A podcast, Dr. Poland also offers information on more COVID-19 studies underway and he talks about COVID-19 vaccine research protocols that will be able to help scientists with other vaccine research, such as HIV vaccine research. Also, he answers listener questions, such as, "Does someone who has already been infected with COVID-19, really need to be fully vaccinated for COVID-19 or would just a booster be needed?"

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline

Guest: Daniel Saris, M.D., Ph.D. (@sarisnl)

Host: Darryl S. Chutka, M.D. (@ChutkaMD)

Osteoarthritis of the knee is extremely common, and it’s estimated that 1 in 2 people are likely to develop symptomatic knee osteoarthritis in their lifetime. Its known that damaged cartilage is the precursor to osteoarthritis. Many individuals have had partial or complete meniscectomies for meniscal tears in the past and those individuals were then likely to eventually develop knee osteoarthritis. What if damaged cartilage was repaired instead of surgically removed? Could that be an effective treatment recommendation we could give to our patients to help prevent or treat osteoarthritis? Our podcast guest today is Dr. Daniel Saris and he has some fascinating information related to cartilage damage and repair using regenerative medicine techniques.

Specific topics discussed:

• How meniscal damage relates to osteoarthritis

 Additional educational opportunities from Mayo Clinic:

• https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Erin K. O'Brien, M.D. (@ErinOBrienMD) 

Host: Amit K. Ghosh, M.D. (@AmitGhosh006) 

Erin O’Brien, M.D., division chair of Rhinology in Rochester, MN, joins us again to provide an evidence-based update on anosmia and its prevalence in post-COVID patients. She reviews the postulated mechanism by which anosmia occurs in this group of patients, and how this effects patients’ safety, mental health, and overall wellbeing. Dr. O’Brien also gives an overview of treatment options, such as various methods of olfactory training, and what physicians need to know when counseling their patients with post-COVID anosmia. 

Additional resources: 

• Video on olfactory training: https://www.youtube.com/watch?v=Qrr0so6pFOs 

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline

Guest: Shane A. Shapiro, M.D. (@ShaneShapiroMD)

Host: Darryl S. Chutka, M.D. (@ChutkaMD)

Musculoskeletal pain is extremely common and when severe, patients often gain significant benefit from joint replacements. However, until our patients reach the point where surgery is an option, our efforts to help patients with the chronic joint pain often leave much to be desired. A relatively new treatment approach has appeared in the past decade, musculoskeletal regenerative medicine. But does the research back up the numerous claims of benefit? This podcast will review the current treatment options available and future potential of regenerative medicine for musculoskeletal problems with Dr. Shane Shapiro, a sports medicine physician in the Department of Orthopedics at the Mayo Clinic. We’ll discuss the current regenerative products and therapies available to optimize patient outcomes, potential adverse effects of the therapies and the numerous claims by many clinicians regarding the benefit potential for regenerative medicine in musculoskeletal disease.

 Specific topics discussed:

• Challenges of currently available traditional treatment for musculoskeletal conditions

 Additional educational opportunities from Mayo Clinic: 

• https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Guest: Tyler S. Oesterle, M.D., M.P.H. (@OesterleMD)

Host: Darryl S. Chutka, M.D. (@ChutkaMD)

Opioid abuse remains a significant problem, and as law enforcement and regulatory agencies tighten access to prescription analgesics, individuals are seeking alternatives. It’s been discovered that when taken at very high doses, loperamide can produce similar effects to the opioid analgesics and the drug is inexpensive when compared to the price of both illicit and prescription opioids. As a result, loperamide abuse has become a significant problem. In this episode we discuss loperamide abuse with Tyler Oesterle, M.D., M.P.H., a psychiatrist at Mayo Clinic’s Rochester campus. We’ll review the typical central nervous system effects of high dose loperamide and the associated safety issues.

Specific topics:

• Current status of the opioid crisis in the U.S.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.