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Dr. Sara Collins joins Dr. Michael Koren to talk about her journey as a research cardiologist. They discuss Dr. Collins's path through preparatory school, college, med school, and the post-school experience as a cardiologist. They also discuss her role starting a clinical research site in Washington, D.C., and her efforts to leverage the research apparatus to provide equitable care to otherwise disadvantaged and underserved communities. Dr. Collins talks about how there is a racial disconnect in care in spite of the typically good insurance coverage in the D.C. area.

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Dr. Michael Koren joins Kevin Geddings to share an anecdote; an acquaintance seemed to put trust in Mel Gibson on a podcast over the American healthcare system. The doctor analyzes why there has been an erosion of trust in this system, why institutions like the medical community and clinical research should be trusted, and how participating in clinical trials can increase your trust in the system as a whole. Dr. Koren also challenges listeners with a specific healthcare biomarker that may be putting your heart at risk.

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Dermatologist and clinical researcher Dr. Michael Bernhardt joins Dr. Erich Schramm to unpack the rapidly evolving science of atopic dermatitis. The two doctors discuss the symptoms, science, and treatments for atopic dermatitis, including how much clinical research has changed the landscape and improved outcomes. The two get into how the immune system drives the disease, and how new therapeutic drugs target those systems in way thats more than just skin deep.

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Dr. Michael Koren joins Kevin Geddings to give thanks this week. The doctor gives gratitude to Kevin, his team, clinical research staff, MedEvidence staff, and most of all, patients. Dr. Koren expresses his heartfelt thanks to everyone who pushes science and research forward!

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Cardiologist Dr. Michael Koren is joined by a 35-year-old patient "Tucker" to walk through his cardiovascular numbers and explain what it all means. The doctor explores a lipid profile and an advanced lipid profile from top to bottom, explaining everything from how LDL is calculated to what hs-CRP measures. Along the way, they discuss how diet, exercise, supplements, and medications can affect these numbers, how the numbers relate to your risk of a cardiovascular event (like a heart attack or stroke) and what, if any, interventions should be taken. This real-world-example shows how complex the world of cardiology and lipids is and gives helpful, actionable information based on the numbers you might see. 

This podcast is not medical advice, and all personal situations should be discussed with your physician.

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Dr. Michael Koren joins Kevin Geddings to discuss some of the pitfalls of traditional healthcare in America and how clinical research can bridge those gaps. The doctor and clinical researcher talks about a family member recieving care in a world-class medical facility, and that even in this setting there is confusion about who is coordinating the patient's care. He contrasts this experience with clinical research, where there are fewer patients and protocol-specified individuals who are required to keep the patient front-of-mind and take charge of medical care.

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Dr. Evan Loh joins Dr. Michael Koren to discuss Dr. Loh's journey through the medical profession. Dr. Loh moved from doing lab work in medical school to patient care in the academic sphere and into the pharmaceutical world of research. Dr. Loh and Dr. Koren discuss the core differences between bedside physican work and research, including in time spent with patients, physician incentives, and the treatment that results. Through it all the doctors find a simple axiom: all medicine is about patients at the end of the day.

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Dr. Koren joins Kevin Geddings to report live from the American Heart Association meeting in New Orleans with fresh results on LDL lowering, prevention, and the future of gene editing for cholesterol. They discuss the excitement of big meetings like the AHA and how results can even surprise the investigators that were working on a study.

Note: Dr. Koren refers to CRISPR Therapeutics, a company developing gene-based cholesterol lowering technologies. CRISPR-Cas9 is also the general name of a gene editing technique.

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Pediatrician and environmental scientist Dr. Deborah Hendrickson joins Dr. Michael Koren to discuss how the environment affects our health. Dr. Hendrickson uses the example of poor air quality from sources such as wildfires and pollution to explain how this impacts children's breathing, from lung development to allergies and asthma. She also notes that the climate is changing due to human causes, which should inspire hope that human solutions are possible. The doctors conclude by discussing how climate change is making things more difficult everywhere and how the risks to our children, in particular, are increasing.

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Dr. Michael Koren joins Kevin Geddings to discuss the current state of COVID vaccines and research. The cardiologist weighs the real risks and benefits of COVID vaccines, focusing on who may need protection the most and who might be able to skip this year's booster. Dr. Koren also talks about the new prescription mandate for COVID vaccines, and how joining a clinical trial may help some people clear that burden more easily.

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