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Proteus was a Greek sea god who could change his form, much like obesity is able to in the body. Doctors Michael Koren, Victoria Helow, and Michael Bernhardt come together in front of a live audience for a discussion on the myriad effects obesity has in and on the body. The doctors move through how excess weight affects the heart, skin, inflammatory systems, and more. They also explain that even when obesity doesn't directly cause a disease is can make other diseases worse. Join these three physician experts to learn why obesity matters

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Dr. Michael Koren is joined by Dr. Ezekiel "Zeke" Emanuel, an oncologist, bioethicist, and former White House advisor. Dr. Emanuel talks about his enduring interest in bioethics and the importance of ethics in areas like clinical research. The two doctors also talk about shared experiences at Harvard Medical School and Dr. Emanuel's contributions to bioethics in healthcare and research over his career. They close Part 1 of this conversation with Dr. Emanuel laying out the disparities between US healthcare spending and health outcomes.

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Dr. Michael Koren joins Kevin Geddings to wax nostalgic about the past generation and what has changed for the better and for the worse. They note that there have been improvements in areas like food, but that air travel and the healthcare experience have deteriorated precipitously. They then contrast this with the massive improvements in the clinical research experience, where around 97-99% of participants say they would do another study. Tune in to find out why this is the case with Dr. Koren and Kevin Geddings.

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Radiologist Sue Jane Grosso-Rivas, MD joins cardiologist and clinical researcher Michael J. Koren, MD for Part Two of her Master's Series on breast imaging.

Dr. Grosso-Rivas talks about some of the complications that can occur during imaging, including dense breasts and their surprising prevalence. She also talks about new technologies in the imaging world, including contrast mammography and the use of AI in cancer detection. She finishes the conversation by talking about men's mammography and the increase in young-onset breast cancer in some populations.

This is part two of a two-part series.

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Dr. Michael Koren joins Kevin Geddings to explain how having a conversation with a medical professional who is tuned into your personal situation can help you understand the confusing and sometimes counterintuitive world of medical information. Cardiologist Dr. Koren uses the examples of coronary calcium scores and total cholesterol levels, which must be interpreted in the context of individual factors, such as age and HDL/LDL ratio. They then discuss clinical research and how the experience in a clinical research setting is one of shared knowledge, where medical professionals take the time to explain everything you need to know about your health.

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Dr. Michael Koren Joins Kevin Geddings to discuss how the current political situation in Washington, D.C. is interfering with clinical research. They discuss the Vaxart trial, that is looking at the next generation of oral COVID vaccines, and how it has been affected by the Trump administration's inconsistent orders regarding vaccines. Dr. Koren points out that the Vaxart trial doesn't actually use mRNA and is poised to be a solution beyond this technology, but that the administration has stopped (at least temporarily) this research anyway.

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Radiologist Sue Jane Grosso-Rivas, MD joins cardiologist and clinical researcher Michael J. Koren, MD to share her inspiring journey from aspiring secretary to Medical Co-Director of Breast Imaging at Summit Health. The doctoral duo discuss how Dr. Grosso-Rivas’s career was shaped by a school counselor who recognized her potential and encouraged her ambition.

Dr. Grosso-Rivas explains the fundamentals of breast mammography: when patients should begin screening, and how to ensure high-quality care for breast cancer prevention. She then explores what happens if mammography finds an abnormality, including if it is benign, suspicious, or indicative of cancer.

This is part one of a two-part series.

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Have a question for Dr. Koren? Email him at [email protected]

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Dermatologist Dr. Kristen Stewart digs deep to get to the root of psoriasis, a skin condition that affects approximately 3% of Americans. She talks about the role of systemic inflammation and how excessive inflammation can impact multiple body systems beyond just the skin. Dr. Stewart reviews her experience treating psoriasis, differentiating it from eczema, and the improvements in modern treatments. Dr. Stewart explains that newer treatment options have revolutionized management approaches, shifting goals from simply reducing symptoms to achieving near-complete clearance and addressing the underlying inflammation.

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Have a question for Dr. Koren? Email him at [email protected]

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The back-to-school season represents an ideal time to reset health priorities and schedules, potentially more impactful than New Year's resolutions. Dr. Michael Koren joins Kevin Geddings to discuss how the changes that come with a new school year also include health changes and the inevitable spread of the flu. They talk about how new initiatives like BARDA, sponsored by the US Department of Health and Human Services, aim to give new ways to fight diseases like the flu in these changing times.

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Have a question for Dr. Koren? Email him at [email protected]

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Cardiothoracic surgeon Dr. Mustafa "Dr. Kurk" Kurkluoglu joins cardiologist Dr. Michael Koren to discuss three mechanisms that affect heart health:

• Oxidative stress, dangerous charged particles that can damage cells
• Inflammation, an immune process that can get out of control
• Endothelial dysfunction, cells that line blood vessels stop working properly

The two doctors discuss what can be done to address some of these issues, including supplements and the evidence  (or lack thereof) supporting their use. Finally, they talk about Dr. Kurk's upcoming book, The Three Musketeers of Heart Health, which is available here.

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