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Benztropine
Trade NameCogentin
IndicationTreatment for Parkinson's disease
ActionExhibits anticholinergic properties (blocks acetylcholine) in the CNS to reduce rigidity and tremors
Therapeutic ClassAntiparkinson agent
Pharmacologic ClassAnticholinergic
Nursing Considerations• May lead to arrhythmias, hypotension, palpitations, and tachycardia • Anticholinergic effects like constipation, dry mouth • Assess for extrapyramidal symptoms • Instruct patient to take as directed • Instruct patient to maintain good oral hygiene
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Zithromax
IndicationURI, chronic bronchitis, lower respiratory infections, otitis media, skin infections, various STIs, prevention of bacterial endocarditis, treatment of cystic fibrosis
ActionInhibits bacterial protein synthesis
Therapeutic ClassAgents for atypical mycobacterium, anti-infectives
Pharmacologic ClassMacrolide
Nursing Considerations• May lead to pseudomembranous colitis, pain, diarrhea, nausea, Stevens-Johnson syndrome, angioedema • May increase risks for warfarin toxicity • Monitor patient for signs of anaphylaxis • Instruct patient to notify physician for diarrhea, or blood or pus in stool • Instruct patient to take medication exactly as prescribed
Lomotil
IndicationTreatment for diarrhea
ActionInhibits GI motility via anticholinergic effects
Therapeutic ClassAntidiarrheal
Pharmacologic ClassAnticholinergic
Nursing Considerations• Contraindicated with angle-closure glaucoma, dehydration • Structurally related to opioids so use caution with patients that have allergies to opioids • May cause constipation, tachycardia, dizziness, ileus • Monitor liver function as the medication is excreted by the liver • Ensure that client is taking medication as prescribed and not double dosing
Atropine
Trade NameAtropen
IndicationDecreases oral and respiratory secretions, treats sinus bradycardia and heart block, treatment of bronchospasm
ActionAtropine is an anticholinergic which means that it inhibits the effects of the parasympathetic nervous system, specifically acetylcholine. This inhibition causes increase in HR, bronchodilation, decreased GI and respiratory secretions.
Therapeutic ClassAntiarrhythmic
Pharmacologic ClassAnticholinergic, antimuscarinic
Nursing Considerations• Avoid in acute hemorrhage, tachycardia, and angle closure glaucoma • Monitor patient for tachycardia and palpitations • May cause urinary retention in elderly patients • Patients may experience constipation due to slowed GI motility
Generic Name
Atenolol
Trade NameTenormin
IndicationHypertension, angina, prevention of MI
ActionBlocks the stimulation of beta1 receptors in the SNS with minimal effect on beta2 receptors
Therapeutic ClassAntianginal, antihypertensive
Pharmacologic ClassBeta blocker
Nursing Considerations• Contraindicated in CHF, pulmonary edema, cardiogenic shock, bradycardia, heart block • Monitor hemodynamic parameters (HR, BP) • May cause bradycardia, CHF, pulmonary edema • Masks symptoms associated with diabetes mellitus • Advise to change positions slowly to prevent orthostatic hypotension • Instruct patient on how to take blood pressure
Acetylsalicylic Acid
Trade NameAspirin
IndicationRheumatoid arthritis, osteoarthritis, ischemic stroke, and MI prophylaxis
ActionInhibits the production of prostaglandins which leads to a reduction of fever and inflammation, decreases platelet aggregation leading to a decrease in ischemic diseases
Therapeutic ClassAntipyretics, non-opioid analgesics
Pharmacologic ClassSalicylates
Nursing Considerations• Use caution in bleeding disorders, chronic alcohol use • May lead to Stevens-Johnson syndrome, laryngeal edema, and anaphylaxis • Increases risk for bleeding with warfarin, heparin, and clopidogrel • Increased risk for GI bleeding with NSAID use • Monitor liver function tests • Concurrent use with alcohol may increase risk for GI bleeding • Aspirin with viral infections can cause Reye's syndrome
Ampicillin
Trade NamePrincipen
IndicationSkin infections, soft tissue infections, otitis media, sinusitis, respiratory infections, GU infections, meningitis, septicemia
ActionBactericidal, broader spectrum than penicillin, binds to cell wall leading to bacterial cell death
Therapeutic ClassAnti-infective
Pharmacologic ClassAminopenicillin
Nursing Considerations• Contraindicated in penicillin allergy, use caution in renal insufficiency • May lead to seizures, diarrhea, anaphylaxis, superinfection • Assess for infection • Monitor liver function tests • Instruct patient on signs of superinfection: furry overgrowth on tongue, vaginal itching, loose and foul smelling stool • Pt should not use with oral contraceptive use.
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