Biykem Bozkurt, MD, PhD, FACC, Editor-in-Chief of JACC: Heart Failure, and Akshay S. Desai, MD, MPH, FACC, Deputy Editor of JACC: Heart Failure interview Andrew J. Sauer, MD, on a state-of the-art review examining the current data on mineralocorticoid antagonism in heart failure, published in JACC: Heart Failure and presented at ESC.