Andy Sudbrock of Sacred Path Retreats joins me on the podcast today to discuss our upcoming Laughter Is Medicine psilocybin mushroom retreat in Jamaica that we're co-hosting at the spectacular Coral Cove Wellness Resort March 15-20 with an afterparty March 20-22.

This retreat is explicitly focused on fun and joy with the assistance of psilocybin mushrooms and a tropical paradise setting: Stand up comedy performances, kayaking, snorkeling, a visit to a world-renowned cannabis farm next door, live music, beach bonfires, and much more all amplified by locally grown Psilocybe cubensis mushrooms in a legal setting.

Learn more about the retreat here

Book your spot at the retreat directly here

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Ted Anderson is the Co-founder of African Rising initiative , a 501(c)(3) non-profit designed to empower African communities through education, sustainable agriculture, women's empowerment, and self-sufficiency skills.

We recorded this episode live in Hoima, Uganda at the Eco-Agric Mushroom Training Center as part of the Third Annual African Rising Mushroom Festival in November, 2025.

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Soren Shade is a drug researcher known for producing Hamilton's Pharmacopeia on Vice and as the Founder of Kratom leaf tea company Top Tree Herbs.

We discuss the evolution of drug markets and policy with a long-view approach beginning in the 1870's and on through today's rapidly shifting drug legislation frameworks globally.

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PsyDAO is a Decentralized Autonomous Community that is funding decentralized psychedelic science and fast-tracking the careers of emergent researchers by investing in their work across multiple early career fellowship projects. Tyler Quigley and Brittney Scott join me today to discuss the function of a DAO, the work they're funding, and how PsyDAO is decoupling psychedelic science and research from limiting patterns that have defined research in the past.

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Dillan DiNardo, Co-Founder and CEO of Mindstate Design Labs, returns to the Mycopreneur Podcast to share updates on the companies progress as a clinical-stage AI neuroengineering platform and drug development outfit. We explore how Mindstate Design is leveraging artificial intelligence in their drug development process, discuss the origins of the company and it's connection to legendary drug chemist Alexander "Sasha" Shulgin, and cover the evolving landscape of psychedelic drug research and where it could all go from here.

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Lee Carroll is the Lead Medical Herbalist at Real Mushrooms and returns to the Mycopreneur Podcast to share updates on his research and journey deeper into the history of traditional mushroom use as well as the modern science to substantiate functional mushroom claims. We discuss mushrooms for longevity, Reishi for heart health, the connection between primates and mushrooms, ways to prevent cognitive decline, and much more.

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James McConchie is the Founder of Haight Street Shroom Shoppe and started cultivating mushrooms years ago to provide access for his wife as she underwent Chemotherapy - today, he stands as one of the most respected and venerable mushroom entrepreneurs in the San Francisco area and beyond. He joins us today to share lessons from 5 years of running the Haight Street Shroom Shoppe, mushroom culture in California's Bay Area and beyond, and his recent research and development into microdosing for dogs alongside Doc Rob silver of Real Mushrooms

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Joshua White of Fireside Project joins us today to share insights about their innovative new "TripCheck" service. TripCheck fills a crucial gap between preparation and real-time crisis support, offering planned wellness check-ins that can prevent challenges from escalating.

We also learn about how Josh found his way into building Fireside Project, the culture of psychedelic use in contemporary society, and more.

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