Featuring articles on evinacumab for familial hypercholesterolemia, the effects of diet vs. gastric bypass in diabetes, drug-coated balloons for dysfunctional dialysis arteriovenous fistulas, fracture risk vs. fracture prevention with bisphosphonates, and the challenges of “return to work” in an ongoing pandemic; a review article on trigeminal neuralgia; a case report of a woman with altered mental status and weakness on the left side; and Perspective articles on low-threshold buprenorphine initiation, on when prescribing isn’t enough, on the death throes of Mercy, and on when the EMR stole a doctor’s pen. Supplement to the New England Journal of Medicine, Vol. 383, No. 8.

Featuring articles on hydroxychloroquine for Covid-19 prophylaxis, subcutaneous or transvenous ICD therapy, Zika virus disease in Colombia, ofatumumab vs. teriflunomide in multiple sclerosis, and spending after state specialty-drug out-of-pocket caps; a review article on native-valve infective endocarditis; a Clinical Problem-Solving on being led astray; and Perspective articles on the National Academy of Medicine and the quality of health care, on care churn, on mental health and the Covid-19 pandemic, and on preventing a parallel pandemic. Supplement to the New England Journal of Medicine, Vol. 383, No. 6.

We discuss the latest in medical research and ideas.

We discuss the latest in medical research and ideas.

We discuss the latest in medical research and ideas.