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Summary:  I received a question about the possible therapeutic pharmacologic benefits of Nicotine, specifically the idea of cutting the Nicotine Patch for help with energy, autoimmune issues, and weight loss.  Answering this question lead into a discussion of new drugs that may emerge from anecdotal evidence.  In this case, how certain elements of Nicotine’s activity might lead to the development of new drugs with neuroprotective and anti-inflammatory effects, without the risks associated with Nicotine use. 

Topics:  

·      Nicotine History 01:20

·      Nicotine Patches, Side Effects 03:00

·      Muscarinic & Nicotinic Receptors 06:00

·      Alzheimers and Parkinson’s Disease in Smokers 08:00

·      Reasoning Toward Possible Uses 09:00

·      CNS & Immune Effects 09:45

·       Rheumatoid Arthritis, Gout, Irritable Bowel Disease/ MS - reduce inflammation   11:00

·      Journavx 11:30

·      Long COVID 12:30

·      Big Pharma Skepticism 15:00

·      Consider the Source 15:50

·      Use Your Pharmacist 17:20

·      For All Drugs:  Potential Benefit/Possible Risks  Decide  Positive Attitude  MONITOR

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