Elena F. Verdu, MD, PhD, co-author of new research on the role of the serine protease inhibitor elafin in celiac disease published in the May 2014 issue of AJG, talks with AJG Co-Editor Dr. William D. Chey about the pathophysiology of celiac disease, the role of various serine proteases, including elafin, in the inflammatory processes of celiac disease, and the potential diagnostic and treatment implications of the study findings. (15:37)