1) Ophelia syndrome and 2) Topic of the month: Hypoxic-ischemic encephalopathy. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jennie Taylor interviews Dr. Josep Dalmau about his paper on Ophelia syndrome. In the next segment, Dr. Jennifer Fugate is reading our e-Pearl of the week about How long must an athlete wait before returning to play after a concussion? In the next part of the podcast Dr. Ted Burns interviews Dr. Eelco Wijdicks about operational issues related to post-cardiac arrest patients. Over the following weeks, Dr. Burns will interview Dr. Wijdicks about neurologic evaluation of the post-cardiac arrest patient. The participants had nothing to disclose except Drs. Dalmau, Fugate, Burns and Wijdicks.Dr. Dalmau serves on the editorial board of Neurology®; receives royalties from the editorial board of Up-To-Date; has filed a patent application for the use of LGI1 as a diagnostic test; has received royalties from Athena Diagnostics, Inc. for a patent re: Ma2 autoantibody test and has patents pending re: NMDA and GABAB receptor autoantibody tests (license fee payments received from EUROIMMUN AG); and receives research support from funding from EUROIMMUN AG, the NIH/NCI, and a McKnight Neuroscience of Brain Disorders award.Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Burns serves as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (30% effort); and has received research support from the Myasthenia Gravis Foundation of America and Knopp Neurosciences Inc..Dr. Wijdicks serves as Editor-in-Chief for Neurocritical Care; and receives royalties for books published by Oxford University Press.