1) Neurodegenerative causes of death and 2) Topic of the month: Encephalopathy caused by systemic disease. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Kutcher interviews Dr. Everett Lehman about his paper on National Football League players. Dr. Stacey Clardy is reading our e-Pearl of the week about the palmonental reflex: Beyond the pain. In the next part of the podcast Dr. Ted Burns interviews Drs. Steven Lewis and Allison Weathers about encephalopathies caused by endocrine disorders. All participants have disclosures.Dr. Kutcher is a consultant for the National Hockey League Players' Association and receives research support from ElMindA, Ltd..Dr. Lehman serves as an editorial board member for Public Health Reports and is Deputy Division Director for the Centers for Disease Control and Prevention (U. S. Federal government).Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Burns serves as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (35% effort); and has received research support for consulting activities with CSL Behring and Alexion Pharmaceuticals.Dr. Lewis serves as CME Section Co-Editor for Neurology® and as Associate Editor for Continuum: Lifelong Learning in Neurology®; receives royalties for the books: Field Guide to the Neurologic Examination and Neurology for the Non-Neurologist and anticipates receiving royalties for the book: Neurologic Disorders due to Systemic Disease.Dr. Weathers receives honoraria as an AAN speaker.