Dr. Nicole Rambo and Sarah discuss Lyme disease in horses, caused by Borrelia burgdorferi transmitted by black-legged ticks, and its growing prevalence in the U.S. They explain that diagnosis is challenging due to vague, variable signs such as shifting lameness, stiffness, behavioral changes, and occasional neurologic cases, with testing options including ELISA/SNAP and the Cornell Multiplex. Treatment typically involves antibiotics like doxycycline or oxytetracycline, alongside careful nutritional management. They emphasize low sugar/starch diets, separating calcium from doxycycline, supporting gut and immune health, managing inflammation with omega-3s, and using natural vitamin E with follow-up testing.

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