1) Indicators of amyloid burden and 2) Topic of the month: Evaluation of polyneuropathy. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns with Dr. Michelle M. Mielke about her paper on indicators of amyloid burden. Dr. Jennifer Fugate is reading our e-Pearl of the week about vestibular migraine. In the next part of the podcast Dr. Ted Burns interviews Dr. Michael Shy about evaluation of the inherited neuropathy patient. The participants had nothing to disclose except Drs. Jeff Burns, Mielke, Fugate, Ted Burns and Shy.Dr. Jeff Burns serves on the editorial board for Journal of Alzheimer's Disease; receives royalties for the publications of Early diagnosis and treatment of mild cognitive impairment and Dementia: An atlas of investigation and diagnosis; is a consultant for PRA International, Johnson County Clinical trials; receives speakers' fees from Novartis Pharmaceuticals Ltd; and receives research support from the NIH, Elan, Janssen Pharmaceuticals Inc., Pfizer Inc, Novartis Pharmaceuticals Ltd and Danone.Dr. Mielke has received research support from the Cynthia and George Mitchell Foundation, Walter S. and Lucienne B. Driskill Foundation and the NIH.Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Ted Burns serves as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (35% effort); and has received research support for consulting activities with CSL Behring and Alexion Pharmaceuticals.Dr. Shy serves as an editorial board member of Journal of Peripheral Nerve System; receives research support from Muscular Dystrophy Association, Charcot Marie Tooth Association and the NIH.