In July 2023, the US Food and Drug Administration (FDA) approved the first oral contraceptive pill (Opill) that will be available without a prescription. JAMA Senior Editor Kristin Walter, MD, MS, spoke with JAMA Associate Editor Melissa A. Simon, MD, MPH, about the use, effectiveness, and potential side effects of Opill. Related Content:

• Over-the-Counter Progestin-Only Oral Contraceptives