In this episode we chat with Associate Professor in the Division of Physical Therapy and the Department of Orthopedic Surgery at University of Kentucky Brian Noehren, PT, PhD, FACSM and Associate Professor Chris Fry, PhD of University of Kentucky in the Department of Athletic Training and Clinical Nutrition. Brian and Chris have a registered (ref. no. NCT03364647), ongoing ACLR trial utilizing BFR where they will be taking serial biopsies to exam what effect the intervention is having upon the quality of the muscle; something they’ve identified to be problematic in previous studies. Here’s a link to their study protocol: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6665950/

The articles we discussed in this episode:

Noehren, B., Andersen, A., Hardy, P., Johnson, D. L., Ireland, M. L., Thompson, K. L., & Damon, B. (2016). Cellular and Morphological Alterations in the Vastus Lateralis Muscle as the Result of ACL Injury and Reconstruction. The Journal of Bone and Joint Surgery. American Volume, 98(18), 1541–1547.

Peck, B. D., Brightwell, C. R., Johnson, D. L., Ireland, M. L., Noehren, B., & Fry, C. S. (2019). Anterior Cruciate Ligament Tear Promotes Skeletal Muscle Myostatin Expression, Fibrogenic Cell Expansion, and a Decline in Muscle Quality. The American Journal of Sports Medicine, 363546519832864.

Noehren, B., & Snyder-Mackler, L. (2020). Who’s Afraid of the Big Bad Wolf? Open-Chain Exercises After Anterior Cruciate Ligament Reconstruction. The Journal of Orthopaedic and Sports Physical Therapy, 50(9), 473–475.

Moro, T., Brightwell, C. R., Phalen, D. E., McKenna, C. F., Lane, S. J., Porter, C., Volpi, E., Rasmussen, B. B., & Fry, C. S. (2019). Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults. Experimental Gerontology, 127, 110723.

Nielsen, J. L., Aagaard, P., Bech, R. D., Nygaard, T., Hvid, L. G., Wernbom, M., Suetta, C., & Frandsen, U. (2012). Proliferation of myogenic stem cells in human skeletal muscle in response to low-load resistance training with blood flow restriction. The Journal of Physiology, 590(17), 4351–4361.

If you’d be interested in pursuing a PhD with these gentlemen feel free to reach out at:

Or, find Brian and Chris on Twitter:

@bnoehren

@ChrisFryPhD

In this episode the fellas discuss a recent paper in the Scandinavian Journal of Medicine & Science in Sports. The paper did a really nice job of refining the work of other authors to remove some bias and give a nice picture of what has been shown thus far as it pertains to the comparison of BFR w/ light weigh to traditional strength training via heavy load.

Grønfeldt, B. M., Lindberg Nielsen, J., Mieritz, R. M., Lund, H., & Aagaard, P. (2020). Effect of blood-flow restricted vs. heavy-load strength training on muscle strength: Systematic review and meta-analysis. Scandinavian Journal of Medicine & Science in Sports. https://doi.org/10.1111/sms.13632

In this episode of the Owens Recovery Science podcast Johnny and Kyle chat with Mark Mañago, PT, DPT, PhD, NCS. Mark is an Assistant Professor in the Physical Therapy program at the University of Colorado Anschutz Medical Campus. Dr. Mañago is a dedicated researcher, focused on advancing clinical research in the field of rehabilitation in people with multiple sclerosis and other neurological conditions by investigating clinically feasible targeted exercise interventions to improve participation. This year, he was awarded a K-12 award through the Comprehensive Opportunities in Rehabilitation Research Training (CORRT) program and recently received a pilot award from the Consortium of MS Centers to study the feasibility of BFR in people with MS.

Papers referenced on this podcast:

Camara-Lemarroy, C., Metz, L., Smith, E., Dunn, J., & Yong, V. W. (2018). Expanding the Potential Therapeutic Options for Remote Ischemic Preconditioning: Use in Multiple Sclerosis. Frontiers in Neurology, 9, 475.

Chotiyarnwong, C., Nair, K., Angelini, L., Buckley, E., Mazza, C., Heyes, D., Ramiz, R., Baster, K., Ismail, A., Das, J., Ali, A., Lindert, R., Sharrack, B., Price, S., & Paling, D. (2020). Effect of remote ischaemic preconditioning on walking in people with multiple sclerosis: double-blind randomised controlled trial. BMJ Neurology Open, 2(1), e000022.

Darvishi, M., Rafiei, M., Kelardeh, B. M., & Keshavarz, S. (n.d.). Effect of Aerobic Training with Blood Flow Restricting on Static Balance, Lower Extremity Strength, and Thigh Hypertrophy in Females with Multiple Sclerosis.

Lamberti, N., Straudi, S., Donadi, M., Tanaka, H., Basaglia, N., & Manfredini, F. (2020). Effectiveness of blood flow-restricted slow walking on mobility in severe multiple sclerosis: a pilot randomized trial. Scandinavian Journal of Medicine & Science in Sports. https://doi.org/10.1111/sms.13764

In this episode we talk with Brad Lambert, PhD of Houston Methodist about their ACLR and throwing shoulder BFR studies, along with his general curiosities and future clinical BFR work. We hope you enjoy the listen! #EARNYOURDEFLATE

In this episode the guys discuss a recent paper evaluating the biomechanical changes that occur when combining BFR with a step up task in healthy subjects and subjects who have had ACLR.

Primary paper:

Telfer, S., Calhoun, J., Bigham, J., Mand, S., Gellert, J., Hagen, M., Kweon, C., & Gee, A. (2020). Biomechanical Effects of Blood Flow Restriction Training after ACL Reconstruction. Medicine and Science in Sports and Exercise. https://doi.org/10.1249/MSS.0000000000002437

Sigward and Chan papers:

Chan, M.-S., & Sigward, S. M. (2019). Loading Behaviors Do Not Match Loading Abilities Postanterior Cruciate Ligament Reconstruction. Medicine and Science in Sports and Exercise, 51(8), 1626–1634.

Chan, M.-S., & Sigward, S. M. (2020). Center of pressure predicts Intra-limb compensatory patterns that shift demands away from knee extensors during squatting. Journal of Biomechanics, 110008.

CRMM paper:

Owens, J. G., Rauzi, M. R., Kittelson, A., Graber, J., Bade, M. J., Johnson, J., & Nabhan, D. (2020). How New Technology Is Improving Physical Therapy. Current Reviews in Musculoskeletal Medicine. https://doi.org/10.1007/s12178-020-09610-6

PT Inquest episode with Susan Sigward:

https://ptpodcast.com/pt-inquest-episode-140-compensatory-strategies-after-aclr/

On this episode of the Owens Recovery Science Podcast Johnny and Kyle chat with Angie West, ATC, John Faltus, PT, ATC and Chad Frazier, ATC. These 3 have worked in some of the coolest areas of musculoskeletal rehabilitation!! They work with circus performers!!

Want to learn even more about performance medicine? Check out their podcast!!

PMED Podcast:

https://podcasts.apple.com/ca/podcast/pmed-podcast/id1516890302

Sound effects and music obtained from https://www.zapsplat.com

In this episode of the ORS podcast Johnny and the fellas discuss a recent paper that has given additional support to the ability of repeated inflations of a cuff limiting muscle atrophy from disuse.

Here’s the paper:

Kakehi, S., Tamura, Y., Kubota, A., Takeno, K., Kawaguchi, M., Sakuraba, K., Kawamori, R., & Watada, H. (2020). Effects of blood flow restriction on muscle size and gene expression in muscle during immobilization: A pilot study. Physiological Reports, 8(14), e14516.

Other papers referenced:

Du Bois, P., Pablo Tortola, C., Lodka, D., Kny, M., Schmidt, F., Song, K., Schmidt, S., Bassel-Duby, R., Olson, E. N., & Fielitz, J. (2015). Angiotensin II Induces Skeletal Muscle Atrophy by Activating TFEB-Mediated MuRF1 Expression. Circulation Research, 117(5), 424–436.

Joshi, S., Wollenzien, H., Leclerc, E., & Jarajapu, Y. P. (2019). Hypoxic regulation of angiotensin-converting enzyme 2 and Mas receptor in human CD34+ cells. Journal of Cellular Physiology, 234(11), 20420–20431.

Tipton, K. D., Hamilton, D. L., & Gallagher, I. J. (2018). Assessing the Role of Muscle Protein Breakdown in Response to Nutrition and Exercise in Humans. Sports Medicine , 48(Suppl 1), 53–64.

Kubota, A., Sakuraba, K., Koh, S., Ogura, Y., & Tamura, Y. (2011). Blood flow restriction by low compressive force prevents disuse muscular weakness. Journal of Science and Medicine in Sport / Sports Medicine Australia, 14(2), 95–99.

Kubota, A., Sakuraba, K., Sawaki, K., Sumide, T., & Tamura, Y. (2008). Prevention of disuse muscular weakness by restriction of blood flow. Medicine and Science in Sports and Exercise, 40(3), 529–534.

What everyone wanted though…the squirrel story!!

https://www.sciencemag.org/news/2019/10/here-s-how-hibernating-squirrels-live-months-without-water

Credit to FoolBoyMedia on free sound.org for the sound byte:

https://freesound.org/s/504687/

In this episode of the Owens Recovery Science podcast we chat with Luke Hughes, PhD about his work thus far in the field on the topics of ACLR rehab with BFR and how BFR influences exercise induced hypoalgesia.

You can find Luke on Twitter at @Luke_H04

Shout out to Brian Goonan, PT aka the Hops and Squats PT for the intro to our podcast today. You can find him on Twitter under the handle @TuneInToGoonan or on Facebook as BK Goon.

Credit to bigmanjoe for his sound clip “Dr. Dre style hip hop loop” serving as the backing track to our podcast intro. You can find bigmanjoe on freesound.org

In this podcast Johnny and the guys chat using BFR on horses with Sherry Johnson, DVM. Dr. Johnson is a specialist in Equine Sports Medicine & Rehabilitation (DACVSMR) and a PhD candidate at Colorado State University where her research is focused on novel rehabilitation modalities related to tendon healing. She is a partner and managing veterinarian of Equine Sports Medicine & Rehabilitation (ESMR). She is also a senior partner and co-founder of Equine CORE, Inc., the nation’s first specialist-owned and operated tele-rehabilitation service.

That’s right people!! Next to, “How the heck does this work above the cuff?” this is easily the most frequently asked question at our courses, “Is it safe in children?”

In this episode we’ve got Adam Weaver, PT and Nick Giampetruzzi, PT from Connecticut Children’s, and Jeannie Graf, PT with Children’s Healthcare of Atlanta on to discuss the research studies that they’re beginning very soon on BFR use following ACLR in adolescents. This is a fun one!! We hope you enjoy!

Connecticut Children’s trial registration:

https://clinicaltrials.gov/ct2/show/NCT04285879?cond=blood+flow+restriction&draw=2&rank=2

Children’s Healthcare of Atlanta trial registration:https://clinicaltrials.gov/ct2/show/NCT04390035?cond=blood+flow+restriction&map_cntry=US&map_state=US%3AGA&draw=2&rank=1

Children's Healthcare of Atlanta Social Media:

FB - @ChildrensHealthcareofAtlanta

IG - @childrensatl

Twitter - @childrensatl

Therapy Dog IG - @TherapyDogsofCHOA

Connecticut Children's Social Media:

Twitter - @ctchildrens

Nick Giampetruzzi, PT:

Twitter - @ngiamPeTruzzi15

Adam Weaver, PT:

Twitter - @adampweaver

IG - @weavera25