Nichole T. Tanner, MD, MSCR, FCCP, and editorialist Jonathan M. Iaccarino, MD, join CHEST Podcast Editor, D. Kyle Hogarth, MD, FCCP, to discuss the accuracy of physician assessment in predicting malignancy in pulmonary nodules. Although adept at recognizing the pretest probability of malignancy, physicians would provide better patient care if they had followed guideline-recommended next steps in evaluation.